在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Selenoprotein S (Sels)

  • 中文名稱:
    小鼠Selenos重組蛋白
  • 貨號(hào):
    CSB-CF857718MO
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Selenos; H47; Vimp; Selenoprotein S; SelS; Minor histocompatibility antigen H47
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    full length protein
  • 表達(dá)區(qū)域:
    1-190
  • 氨基酸序列
    MDRDEEPLSARPALETESLRFLHVTVGSLLASYGWYILFSCILLYIVIQRLSLRLRALRQ RQLDQAETVLEPDVVVKRQEALAAARLRMQEDLNAQVEKHKEKLRQLEEEKRRQKIEMWD SMQEGRSYKRNSGRPQEEDGPGPSTSSVIPKGKSDKKPLRGGGYNPLTGEGGGTCSWRPG RRGPSSGGUN
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
  • 基因功能參考文獻(xiàn):
    1. findings suggest that SelS protects endothelial cells against TNF-alpha-induced dysfunction by inhibiting the activation of p38 MAPK and NF-kappaB pathways and implicates it as a possible modulator of vascular inflammatory diseases. PMID: 29805311
    2. the genetic reduction of Seps1 appears to specifically exacerbate the inflammatory profile of fast-twitch muscle fibres, which are typically more vulnerable to degeneration in dystrophy. PMID: 28592916
    3. Pro(178) and Pro(183) of SelS play important roles in the translocation of p97(VCP) to the ER membrane and protect cells from ER stress PMID: 24700463
    4. SelS expression is prominent in neurons and hardly detectable in astrocytes from control mice PMID: 21456042
    5. The SEPS1 protein expression in liver of septic mouse is markedly elevated. PMID: 20979832
    6. Selenoprotein biosynthesis becomes redirected in hepatocytes during the acute-phase response at the expense of dispensable selenoproteins (e.g., SepP) and in favor of SepS expression, thereby causing declining serum selenium and improving liver function. PMID: 20370716
    7. These findings suggest that SEPS1 could be a new ER stress-dependent survival factor that protects macrophage against ER stress-induced cellular dysfunction. PMID: 17210132
    8. We found that suppression of SEPS1 by small interfering RNA severely increases astrocyte injure caused by OGD, suggesting that selenoprotein S protects astrocytes against ischemia. PMID: 18498015

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm.
  • 蛋白家族:
    Selenoprotein S family
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 亚洲精品久久久久久久观小说 | 成人无码www在线看免费| 强制高潮18xxxx按摩| av国産精品毛片一区二区视频 | 业余 自由 性别 成熟视频 视频| 未满十八勿入av网免费| 亚洲精品专区成人网站| 亚洲成a人v欧美综合天堂| 九九热在线视频观看这里只有精品| 无码欧美黑人xxx一区二区三区| 亚洲成av 人片在线观看无码| 图片区小说区另类春色| 国产成人免费永久在线平台| 日韩欧美人妻一区二区三区| 中国国产免费毛卡片| 免费三级现频在线观看播放| 国产又黄又大又粗视频| 欧美人与动人物牲交免费观看久久| 性强烈的欧美三级视频| 精品国产乱码久久久软件下载| 无码人妻一区二区三区免费手机| 少妇挑战三个黑人惨叫4p国语| 激情综合色五月六月婷婷| 国产99在线 | 中国| 国产 | 久你欧洲野花视频欧洲1| 精品三级av无码一区| 亚洲已满18点击进入在线观看| 国产日产精品一区二区三区四区的特点 | 岛国无码av不卡一区二区| 欧洲av无码放荡人妇网站| 欧美xxxx做受欧美| 真人做人60分钟啪啪免费看 | 欧美毛多水多肥妇| 国产97色在线 | 日韩| 日本护士毛茸茸xx| 四虎影视永久免费观看在线| 黑人粗硬进入过程视频| 亚洲欧美日韩国产综合v| 688欧美人禽杂交狂配| 国产免费拔擦拔擦8x高清在线人| 亚在线观看免费视频入口|