在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse RING finger protein 112 (Rnf112)

  • 中文名稱:
    小鼠Rnf112重組蛋白
  • 貨號:
    CSB-CF019818MO
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
    Rnf112
  • Uniprot No.:
  • 別名:
    Rnf112; Bfp; Znf179; RING finger protein 112; Brain finger protein; Neurolastin; Zinc finger protein 179
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-654
  • 氨基酸序列
    MPRPVLSVTAFCHRLGKRESKRSFMGNSSNSWVLPREEAQGWMGQAVQGGTRTSRSHASF PKLELGLGHRPSPTREPPTCSICLERLREPISLDCGHDFCIRCFSTHRIPGCELPCCPEC RKICKQRKGLRSLGERMKLLPQRPLPPALQETCAVRAERLLLVRINASGGLILRMGAINR CLKHPLARDTPVCLLAVLGEQHSGKSFLLDHLLSGLPSLESGDSGRPRAEGSLPGIRWGA NGLTRGIWMWSHPFLLGKEGKKVAVFLVDTGDVMSPELSKETRVKLCALTMMLSSYQILN TSQELKDTDLGYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHHNKSGQGHVGDILQKL SGKYPKVQELLLGKRARCYLLPAPERQWVNKDQASPRGNTEDDFSHHFRAYILDVLSTAP QHAKSRCQGYWSEGRAVARGDRRLLTGQQLAQEIKNLSGWMGKTGPSFNSPDEMAAQLHD LRKVEAAKKEFEEYVRQQDIATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKER EQTLEALEAELQAEAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAA EAGMVAAGAAVGATGAAVVGGGVGAGLAATVGCMEKEEDERVQGGDREPLLQEE
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage. Exhibits GTPase and E3 ubiquitin-protein ligase activities. Regulates dendritic spine density and synaptic neurotransmission; its ability to hydrolyze GTP is involved in the maintenance of dendritic spine density.
  • 基因功能參考文獻:
    1. Rnf112 protein is expressed in most brain areas and mainly in neurons; deletion of both Rnf112 alleles resulted in embryonic lethality associated with defects in embryonic vasculature; results provide evidence for the important functions of Rnf112 in embryo development and in adult brain PMID: 26951452
    2. Study focused on sigma-1 receptor (Sig-1R), a chaperone at endoplasmic reticulum, and investigated its protective functions; results reveal that zinc finger protein 179 plays a novel role in neuroprotection. PMID: 26792191
    3. identify neurolastin as a dynamin family GTPase that affects endosome size and spine density. PMID: 26212327
    4. This study provides the first evidence that ZNF179, PLZF, IGFBP3, and BIK contributed to the novel CEBPD-induced antiapoptotic feature of astrocytes. PMID: 24788683
    5. Induction of the Znf179 gene is associated with p35 expression and p27 protein accumulation, which lead to cell cycle arrest in the G0/G1 phase, and is critical for neuronal differentiation of P19 cells. PMID: 21566658

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Multi-pass membrane protein. Membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Nucleus, nuclear body. Nucleus, nucleoplasm. Endosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cell junction, synapse, postsynaptic density. Perikaryon. Cell projection, neuron projection.
  • 蛋白家族:
    TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily
  • 組織特異性:
    Expressed in most of the brain areas, including cortex, striatum, hippocampus, thalamus, and cerebellum (at protein level). Expressed in lateral amygdaloid nucleus, and ventromedial hypothalamus. Also expressed strongly in the marginal zone of brain vesic
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 免费毛儿一区二区十八岁| 色偷偷亚洲精品一区二区| 好吊射视频988gaocom| 欧美午夜成人片在线观看| 国产特级毛片aaaaaa高潮流水| 男女超爽视频免费播放| 自拍校园亚洲欧美另类| 国产真实露脸乱子伦 | 双腿张开被9个男人调教| 忘忧草日本在线播放www| 午夜福利视频1692| 国产一精品一av一免费| 精品人妻少妇嫩草av无码专区| 日韩人妻无码精品专区906188| 99久re热视频这里只有精品6 | 妓院一钑片免看黄大片| 男人扒开女人内裤强吻桶进去| 97无码精品综合| 中文字幕亚洲码在线观看| 亚洲精品国产精品国自产| 四虎国产精品亚洲一区久久特色 | 小说区 图片区色 综合区| 国产成人av无码精品天堂| 午夜无码片在线观看影院y| 中文字幕无码家庭乱欲| 日日碰狠狠躁久久躁蜜桃| 日韩人妻熟女中文字幕a美景之屋| 麻豆国产在线精品国偷产拍| 国产超碰人人做人人爱| 国产成人亚洲综合| 真人抽搐一进一出gif| 成年女人永久免费看片| 大屁股熟女一区二区三区| 欧美性大战xxxxx久久久| 色一情一伦一区二区三| 野外少妇激情aa 级视频| 五月丁香六月综合av| 欧美zozo另类特级| 国产深夜福利视频在线| 无码人妻精品中文字幕免费东京热| 亚洲精品午夜无码专区|