在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse N-arachidonyl glycine receptor (Gpr18)

  • 中文名稱:
    小鼠Gpr18重組蛋白
  • 貨號:
    CSB-CF810372MO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Gpr18; N-arachidonyl glycine receptor; NAGly receptor; G-protein coupled receptor 18
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-331
  • 氨基酸序列
    MATLSNHNQLDLSNGSHPEEYKIAALVFYSCIFLIGLFVNVTALWVFSCTTKKRTTVTIY MMNVALLDLVFILSLPFRMFYYAKGEWPFGEYFCHILGALVVFYPSLALWLLAFISADRY MAIVQPKYAKELKNTGKAVLACGGVWVMTLTTTVPLLLLYEDPDKASSPATCLKISDITH LKAVNVLNFTRLIFFFLIPLFIMIGCYVVIIHSLLRGQTSKLKPKVKEKSIRIIMTLLLQ VLVCFVPFHICFAVLMLQGQENSYSPWGAFTTFLMNLSTCLDVVLYYIVSKQFQARVISV MLYRNYLRSVRRKSVRSGSLRSLSNMNSEML
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for endocannabinoid N-arachidonyl glycine (NAGly). However, conflicting results about the role of NAGly as an agonist are reported. Can also be activated by plant-derived and synthetic cannabinoid agonists. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system. Is required for normal homeostasis of CD8+ subsets of intraepithelial lymphocytes (IELs) (CD8alphaalpha and CD8alphabeta IELs) in small intstine by supporting preferential migration of CD8alphaalpha T-cells to intraepithelial compartment over lamina propria compartment, and by mediating their reconstitution into small intestine after bone marrow transplant. Plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure. Mediates NAGly-induced process of reorganization of actin filaments and induction of acrosomal exocytosis.
  • 基因功能參考文獻:
    1. Our results support FAAH-dependent NAGly action at GPR18 as the physiologic basis of the diurnal variation of intraocular pressure in mice. PMID: 27893106
    2. GPR18 has a role in the development and reconstitution of thymus-derived intestinal IEL subsets in the steady-state and after bone marrow transplantation PMID: 26197390
    3. Data indicate that orphan G-protein-coupled receptor GPR18 is required for the normal homeostasis of CD8alphaalpha gammadeltaT and alphabetaT and CD8alphabeta intestinal intraepithelial lymphocyte compartment. PMID: 25348153
    4. Data (including data from knockout mice) suggest that signal transduction involving GPR18 in corneal epithelium and ciliary epithelium is required for regulation of intraocular pressure. PMID: 23461720
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Expressed in the eye including cornea, retina, iris and ciliary epithelium (at protein level). Expressed in spleen, liver and lymphocytes with highest expression levels in intestinal intraepithelial lymphocytes.
  • 數據庫鏈接:


主站蜘蛛池模板: 中国老妇xxxx性开放| 中文字幕无码av正片| 最新无码人妻在线不卡| 亚洲综合成人av一区在线观看| 无码人妻一区二区三区线| 国产精品自在在线午夜出白浆| 欧美黑人异族videos| 成人无码午夜在线观看| 午夜福利无码不卡在线观看| 国产精品熟妇视频国产偷人| 人妻三级日本香港三级极| 亚洲成a人片在线观看天堂无码不卡| 极品人妻videosss人妻| 人人妻人人澡人人爽人人精品浪潮 | 无码免费中文字幕视频| 免费观看黄网站| 国产精品久久久久久影视| 色多多成视频人在线观看| 精品无码久久久久久尤物| 成人区人妻精品一区二区三区| 夜夜爽一区二区三区精品| 亚洲综合区小说区激情区| 中文无码日韩欧免费视频| 少妇被猛男粗大的猛进出| 好了av四色综合无码久久| 第一亚洲中文久久精品无码| 国产 亚洲 制服 无码 中文 | 欧洲无码精品a码无人区| 久久精品超碰av无码| 欧洲乱码伦视频免费| 中文乱码字幕视频观看网站免费| 日韩欧美亚洲综合久久影院ds| 无码视频在线观看| 欧美一区二区三区激情| 欧美日激情日韩精品嗯| 日本xxx在线观看免费播放| 国产肥白大熟妇bbbb视频| 麻豆精产一二三产区| 衣服被扒开强摸双乳18禁网站| 亚洲中文字幕无码爆乳av| 亚洲 日韩 国产 中文有码|