在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Mucolipin-2 (Mcoln2)

  • 中文名稱:
    小鼠Mcoln2重組蛋白
  • 貨號:
    CSB-CF815689MO
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    Mcoln2
  • Uniprot No.:
  • 別名:
    Mcoln2; Mucolipin-2; Transient receptor potential channel mucolipin 2; TRPML2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-566
  • 氨基酸序列
    MPGDEETLDLPAWNRVPDLTWGPHHRSAMASLDSEVREECLREDLKFYFMSPCEKYRARR QIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGFSGVDEDDYSCS IYTQENTYESIFFAIKQYRHLKNISLATLGYGESEDNRTGLKVCKQHYKTGAMFSSNETL NIDSDIETDCIHLDLQVLTTEPEDWAQTSFFRLDFYRLVQVDISFALKGIDLQAVHSREI PDCYLFQNTITFDNTAHSGKIKIYLNSEANIEECKNMNISGSTQRSTHYLLVFDVFVIMI CLASLILCTRSIVLALRLRKRFLNFFLEKYKQRVCGADQWEFVNGWYVLVTISDLMTIIG SILKMEIKAKKLTNYDVCSILLGTSTLFVWVGVIRYLGYFQTYNVLILTMQASLPKVLRF CACAGMIYLGYTFCGWIVLGPYHEKFENLNIVAECLFSLVNGDDMFATFAQIQQKSILVW LFSRLYLYSFISLFIYMVLSLFIALITDSYHTIKKYQQHGFPETDLQKFLKESGSKDGYQ KQPSALLSCLCCLRRRRSNDHLILID
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Nonselective cation channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)-permeable cation channel with inwardly rectifying activity. May activate ARF6 and be involved in the trafficking of GPI-anchored cargo proteins to the cell surface via the ARF6-regulated recycling pathway. May play a role in immune processes. In adaptive immunity, TRPML2 and TRPML1 may play redundant roles in the function of the specialized lysosomes of B cells. In the innate immune response, may play a role in the regulation of chemokine secretion and macrophage migration. Through a possible and probably tissue-specific heteromerization with MCOLN1 may be at least in part involved in many lysosome-dependent cellular events.
  • 基因功能參考文獻:
    1. study reveals interesting differences in the regulation and distribution of the members of the TRPML family and identifies a novel role for TRPML2 in the innate immune response. PMID: 26432893
    2. Expressed in both B-cell lines and primary B-lymphocytes. PMID: 16137664
    3. there is a hierarchy controlling the subcellular distributions of the TRPMLs such that TRPML1 and TRPML2 dictate the localization of TRPML3 and not vice versa PMID: 16606612
    4. TRPML1 appears to play a novel role in the tissue-specific transcriptional regulation of TRPML2. PMID: 19763610
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Transient receptor (TC 1.A.4) family, Polycystin subfamily, MCOLN2 sub-subfamily
  • 組織特異性:
    Isoform 1 is widely expressed at very low levels. Isoform 2 is expressed at high levels in lymphoid tissues (thymus and spleen) and kidney, and at moderate levels in heart, lung, liver and stomach. Expressed in activated macrophages and microglia (at prot
  • 數據庫鏈接:


主站蜘蛛池模板: 中国丰满少妇人妻xxx性董鑫洁 | 五级黄高潮片90分钟视频| 久久婷婷久久一区二区三区| 国产日产欧产精品精品app| 2022一本久道久久综合狂躁| 久久久久久a亚洲欧洲av冫| 性色av免费观看| 国产真实乱人偷精品视频| 在线 偷窥 制服 另类 | 国产百合互慰吃奶互揉视频| 国产大陆亚洲精品国产| 无码人妻精品中文字幕免费东京热 | 波多野结衣在线精品视频| 中文在线а天堂| 最近中文字幕免费mv在线 | 亚洲最新版av无码中文字幕| 在线|国产精品女主播阳台| 日韩v亚洲v欧美v精品综合| 国产成人精品视频ⅴa片软件竹菊| 中文字幕乱妇无码av在线| 亚洲人成电影网站色迅雷| 亚洲v欧美v日韩v国产v| 欧美日韩亚洲中文字幕一区二区三区| 成人动漫综合网| 精品人妻一区二区三区四区在线| 奇米777国产在线视频| 欲色欲色天天天www| 国产欧美在线观看不卡| 美女张开腿黄网站免费下载| 亚洲国产欧美在线看片一国产| 伦埋琪琪久久影院三级| 欧美s码亚洲码精品m码| 久久久久国产一区二区| 亚洲2021av天堂手机版| 亚洲一卡2卡3卡4卡5卡精品| 亚洲蜜桃精久久久久久久久久久久| 亚洲国产精品久久精品| 日本午夜免费啪视频在线| 娜娜麻豆国产电影| 亚洲高清毛片一区二区| 女人裸体做爰免费视频|