在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse G-protein coupled receptor 3 (Gpr3)

  • 中文名稱:
    小鼠Gpr3重組蛋白
  • 貨號:
    CSB-CF009800MO
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Gpr3; Gpcr3; G-protein coupled receptor 3; GPCR21
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full length protein
  • 表達區(qū)域:
    1-330
  • 氨基酸序列
    MMWGAGSSMAWFSAGSGSVNVSSVDPVEEPTGPATLLPSPRAWDVVLCISGTLVSCENAL VVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAADFCIGSPEMSLMLVGVLAMAF TASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWVGALGLGLVPVLAWNCRDG LTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYV ATRKGIATLAVVLGAFAACWLPFTVYCLLGDADSPRLYTYLTLLPATYNSMINPVIYAFR NQDVQKVLWAICCCCSTSKIPFRSRSPSDV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavioral responses to stress, amyloid-beta peptide generation in neurons and neurite outgrowth. Maintains also meiotic arrest in oocytes.
  • 基因功能參考文獻:
    1. These results demonstrate that GPR3 potentiates meiotic competence, most likely by raising cAMP. PMID: 29274320
    2. GPR3 appears to have a key role in the thermogenic response of interscapular brown adipose tissue and may represent a new therapeutic target in age-related obesity. PMID: 26455425
    3. This study found that the expression of GPR3 in CGNs exerted prosurvival effects against apoptosis-inducing stimuli, such as potassium deprivation, hypoxia, and ROS. PMID: 24769160
    4. Altered signalling pathways of GPR3 could contribute to the neurobiological substrate involved in developing addiction to cocaine PMID: 22612385
    5. Involvement of the orphan GPR3 receptor is demonstrated for the first time in expression and development of neuropathic pain and in analgesia induced by morphine. PMID: 21352831
    6. the GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle and is crucial for the regulation of meiosis PMID: 15591206
    7. Gpr3-defective mice may constitute a relevant model of premature ovarian failure due to early oocyte aging. PMID: 15956199
    8. GPR3 specifically in the oocyte, rather than in the follicle cells, is responsible for maintenance of meiotic arrest in mouse oocytes. PMID: 16289135
    9. GPR3-G(s) activation in response to stimulation of an exogenously expressed beta(2)-adrenergic receptor causes Galpha(s) to move from the oocyte plasma membrane into the cytoplasm. PMID: 17850783
    10. Gpr3 is epistatic to Pde3a and fertility as well as meiotic arrest in the PDE3A-deficient oocyte is dependent on the activity of GPR3. PMID: 18280465
    11. GPR3 qualifies as a new player in the modulation of behavioral responses to stress and constitutes a novel promising pharmacological target for treatment of emotional disorders PMID: 19259266
    12. GPR3 is a novel antiproliferative mediator of CGPs in the postnatal development of murine cerebellu PMID: 19526062

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Expressed in both the forebrain and hindbrain, with the highest level in habenula. Lower level expression in the testis. Highly expressed in regions.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 人人爽人人爽人人片av| 国产人妻人伦精品| 2020无码专区人妻系列日韩| 久久久久人妻精品一区三寸蜜桃| 国产成人精品无码专区| 偷看农村妇女牲交| 成年片色大黄全免费网站久久| 18禁成人黄网站免费观看久久 | 99精品免视看| 激情久久av一区av二区av三区| 怡红院免费的全部视频| 国产亚洲精品久久久久久国| 999国内精品永久免费观看| 日日天干夜夜狠狠爱| 亚洲小说区图片区另类春色| 人妻出轨av中文字幕| 强奷妇系列中文字幕| 亚洲婷婷综合色高清在线| 国产青草视频在线观看| 日韩午夜理论免费tv影院| 2020久热爱精品视频在线观看| 少妇高潮喷水久久久影院| 男女同房做爰爽免费| 久久精品国产只有精品96| 老熟女高潮喷水了| 欧美老肥妇做爰bbww| 国产一区二区三区在线电影| 久久久中日ab精品综合 | 国产综合在线观看| 国产亚洲福利在线视频| 人妻插b视频一区二区三区| 国产亚洲视频中文字幕97精品| 中文字幕人成乱码熟女香港| 极品少妇被猛得白浆直喷白浆小说| 国产交换配乱婬视频| 国产成a人亚洲精品无码樱花| 婷婷色爱区综合五月激情| 精品国产成人高清在线观看| 欧美成人精品三级网站| 精品国内自产拍在线播放观看| 亚洲欧美中文高清在线专区|