在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse FUN14 domain-containing protein 1 (Fundc1)

  • 中文名稱:
    小鼠Fundc1重組蛋白
  • 貨號:
    CSB-CF861601MO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Fundc1; FUN14 domain-containing protein 1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-155
  • 氨基酸序列
    MASRNPPPQDYESDDESYEVLDLTEYARRHHWWNRVFGHSSGPMVEKYSVATQIVMGGVT GWCAGFLFQKVGKLAATAVGGGFLLLQVASHSGYVQIDWKRVEKDVNKAKRQIKKRANKA APEINNIIEEATDFIKQNIVISSGFVGGFLLGLAS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control.
  • 基因功能參考文獻:
    1. By facilitating Mff-mediated mitochondrial fission and FUNDC1-required mitophagy, NR4A1 disturbed mitochondrial homeostasis, enhanced endothelial apoptosis and provoked microvascular dysfunction in myocardial ischemia reperfusion injury. PMID: 29744594
    2. FUNDC1 is required for cardiac ischemia reperfusion injury activated mitophagy. PMID: 28732308
    3. hypoxic preconditioning induces FUNDC1-dependent mitophagy in platelets and reduces Ischemia/Reperfusion-induced heart injury, suggesting a new strategy to protect cardiac function and fight cardiovascular diseases. PMID: 28323531
    4. FUNDC1 binds to IP3R2 to modulate ER Ca(2+) release into mitochondria and cytosol. Disruption of the FUNDC1 and IP3R2 interaction lowers the levels of Ca(2+) in mitochondria and cytosol, both of which instigate aberrant mitochondrial fission, mitochondrial dysfunction, cardiac dysfunction, and heart failure. PMID: 28942427
    5. MicroRNA-137 has a role in inhibiting mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX PMID: 24573672

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion outer membrane; Multi-pass membrane protein.
  • 蛋白家族:
    FUN14 family
  • 數據庫鏈接:


主站蜘蛛池模板: 精品国产品香蕉在线| 人妻少妇偷人无码视频| 国产亚洲精品视觉盛宴| 成人免费ā片在线观看| 免费午夜爽爽爽www视频十八禁 | 人妻少妇heyzo无码专区 | 宅宅午夜无码一区二区三区| 国产亚洲精品久久久久久老妇小说| 成人天堂资源www在线| 国产精品理论片在线观看| 欧美人禽杂交狂配免费看| 无码av专区丝袜专区| 国产亚洲视频中文字幕97精品| 成人综合婷婷国产精品久久| 久久国产精品免费一区| 韩国精品视频一区二区在线播放| 欧美颜射内射中出口爆在线| 中文在线中文a| 久久国产精品日本波多野结衣| 国产真实的和子乱拍在线观看| 疯狂撞击丝袜人妻| 亚洲狠狠色成人综合网| 亚洲精品久久av无码麻| 激情人妻另类人妻伦| 欧洲多毛裸体xxxxx| 亚洲中文有码字幕青青| 果冻传媒18禁免费视频| 成人性生交片无码免费看| 色8激情欧美成人久久综合电影| 久久亚洲色www成人不卡| 色窝窝免费一区二区三区| 成人h动漫精品一区二区| 2020年无码国产精品高清免费| 精品无码久久久久国产| 精品久久久久成人码免费动漫| 亚洲欧洲自拍拍偷精品 美利坚| 亚洲中字慕日产2020| 人妻 色综合网站| 国产98色在线 | 国| 香港日本三级亚洲三级| a欧美爰片久久毛片a片|