在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse B-cell antigen receptor complex-associated protein beta chain (Cd79b)

  • 中文名稱:
    Recombinant Mouse B-cell antigen receptor complex-associated protein beta chain(Cd79b)
  • 貨號:
    CSB-CF004958MO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Cd79b; Igb; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD antigen CD79b
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    26-228
  • 氨基酸序列
    VPAMTSSDLPLNFQGSPCSQIWQHPRFAAKKRSSMVKFHCYTNHSGALTWFRKRGSQQPQELVSEEGRIVQTQNGSVYTLTIQNIQYEDNGIYFCKQKCDSANHNVTDSCGTELLVLGFSTLDQLKRRNTLKDGIILIQTLLIILFIIVPIFLLLDKDDGKAGMEEDHTYEGLNIDQTATYEDIVTLRTGEVKWSVGEHPGQE
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
  • 基因功能參考文獻:
    1. ablation of B cell antigen receptor ubiquitination in vivo uncouples the receptor from CD19 phosphorylation and phosphatidylinositol 3-kinase (PI3K) signals. PMID: 29141870
    2. B-cell inhibition by cross-linking CD79b is superior to B-cell depletion with anti-CD20 antibodies in treating murine collagen-induced arthritis. PMID: 25471597
    3. The cytoplasmic tail of IgG1 is strictly required for the surface expression of IgG1 when the expression of Iga/Igb heterodimer is down-regulated in B lymphoma. PMID: 24548411
    4. describe a novel mouse with a spontaneous mutation in the Cd79b gene leading to a block in B-cell development and agammaglobulinemia. PMID: 19727123
    5. The VHDJH recombination process at the IgH locus and the survival of pro-B cells that carry these rearrangements do not depend on the expression of Ig-beta molecules. PMID: 12097390
    6. Deletion in developing B cells leads to cell death; Igbeta expression is essential to maintain preB cell and immature B cell survival and to mediate B cell differentiation PMID: 12165571
    7. Spontaneous mutation in the Cd79b gene leads to a block in B-lymphocyte development at the C' (early pre-B) stage PMID: 19727123

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
  • 組織特異性:
    B-cells.
  • 數據庫鏈接:


主站蜘蛛池模板: 一边添奶一边添p好爽视频 | 午夜伦yy44880影院| 亚洲人成无码www久久久| 极品无码av国模在线观看| 黑人巨大av在线播放无码| 欧美饥渴熟妇高潮喷水水| 少妇精品无码一区二区三区| 免费人成视频网站在线下载| 99久热国产精品视频尤物| 欧美另类精品xxxx| 毛片免费视频观看| av淘宝国产在线观看| 亚洲精品久久久久久成人| 久久国国产免费999| 在线观看午夜亚洲一区| аⅴ资源中文在线天堂| 人妻被按摩师玩弄到潮喷| 亚洲大色堂人在线无码| 久久综合九色综合欧洲98| 少妇粉嫩小泬白浆流出| 国产av无码专区亚洲awww| 亚洲国产精品日韩av不卡在线| 鲁一鲁av2019在线| 色久悠悠婷婷综合在线亚洲 | 国产在线aaa片一区二区99| 日日噜噜夜夜狠狠久久无码区| 激情文学小说区另类小说同性| 天堂中文官网在线| 韩国美女视频黄是免费| 亚洲国产午夜精华无码福利 | 久久午夜夜伦鲁鲁片免费无码| 日本老熟妇乱| av毛片无码中文字幕不卡| 日本xxxx片免费观看| 狠狠色婷婷久久一区二区三区| 欧美成人免费全部观看国产| 无码一卡二卡三卡四卡| 亚洲精品一区二区三区四区乱码| 都市激情 在线 亚洲 国产| 国语自产精品视频在 视频| 护士被强女千到高潮视频|