在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Atrial natriuretic peptide receptor 3 (Npr3)

  • 中文名稱:
    小鼠Npr3重組蛋白
  • 貨號:
    CSB-CF016025MO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Npr3; Atrial natriuretic peptide receptor 3; Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor type C; ANP-C; ANPR-C; NPR-C; EF-2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    41-536
  • 氨基酸序列
    EALAAQKIEVLVLLPRDDSYLFSLARVRPAIEYALRSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSAYNFDETKDLDLDDIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGMTSGDYAFFNIELFNSSSYGDGSWRRGDKHDSEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNEEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVVAMTDTEAGTQEVIGDYFGKEGRFQMRSNVKYPWGPLKLRLDETRIVEHTNSSPCKSSGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRNQQEESNIGKHRELREDSIRSHFSVA
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
  • 基因功能參考文獻:
    1. this study shows that sensory axon bifurcation is insensitive to increases of C-type natriuretic peptide induced cyclic GMP levels and the guanylate cyclase receptor Npr3 does not have an important scavenging function in this axonal system. PMID: 27740716
    2. A model of kyphosis due to a novel NPR3 Tyr209Asn mutation is established. PMID: 27959934
    3. Npr3 is expressed in hard calluses of wild-type mice, suggesting a possible role of CNP signaling in fracture repair, especially in bone remodeling stage. PMID: 25860030
    4. NPR-C is required to control DNA damage-induced p53 levels to maintain embryonic stem cell self-renewal. PMID: 21846177
    5. A stratified transcriptomics analysis of polygenic fat and lean mouse adipose tissues identifies Npr3 as novel candidate obesity genes. PMID: 21915269
    6. Upregulation of NPR-C mRNA in the kidney and heart of eNOS knockout mice. PMID: 20403400
    7. CNP has negative chronotropic effect on heart rate, and this effect is mediated by selectively activating NPR-C and reducing L-type Ca2+ current through coupling to Gi protein. PMID: 14704228
    8. discussion of neuronal regulation and function of natriuretic peptide receptor C [review] PMID: 15911073

    顯示更多

    收起更多

  • 相關疾病:
    Defects in Npr3 are the cause of a number of skeletal-overgrowth phenotypes, Longjohn (Lgj), Longjohn-2J (Lgj-2J) and Strigosus (Stri). These are all recessive conditions characterized by an elongated body, thoracic kyphosis, arachnodactyly, and sacral and/or tail kinks, but no significant changes in craniofacial structures (PubMed:10468599).
  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    ANF receptor family
  • 數據庫鏈接:


主站蜘蛛池模板: 久9热视频这里只精品18| 亚洲高清无在码在线电影不卡| 久章草在线精品视频免费观看 | 国产亚洲视频中文字幕97精品| 中文字幕无线码| 樱花草在线社区www中国中文| 国产亚洲精品福利视频| 色在线亚洲视频www| 97久久精品人人做人人爽| 久久综合伊人77777| 亚洲成色在线综合网站| 国产精品人成在线播放新网站| 人妻av无码系列一区二区三区| 久久精品噜噜噜成人av| 少妇私密会所按摩到高潮呻吟| 欧美老肥妇做爰bbww| av天堂永久资源网亚洲高清| 久九九精品免费视频| 国产成年无码久久久久毛片| 成人无码一区二区三区| 先锋影音xfyy5566男人资源| 夜夜澡天天碰人人爱av | 国产精品亚洲二区在线观看| 使劲快高潮了国语对白在线| 日韩欧美一中文字暮专区| 久久精品aⅴ无码中文字字幕不卡| 亚洲精品成人av在线观看爽翻天| 天天鲁一鲁摸一摸爽一爽| 麻批好紧日起要舒服死了| 色 成人 亚洲| 艳妇乳肉豪妇荡乳在线观看| 天美麻花果冻视频大全英文版| 国产免国产免费| 精品麻豆丝袜高跟鞋av| 巨熟乳波霸若妻在线播放| 无码中文字幕乱在线观看| 国产精品自在欧美一区| 久久亚洲精品国产精品777777| 亚洲精品专区成人网站| 国产精品久久久久影院老司| 国产精品久久久久久久9999|