在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Aquaporin-7 (Aqp7)

  • 中文名稱:
    Recombinant Mouse Aquaporin-7(Aqp7)
  • 貨號(hào):
    CSB-CF001967MO
  • 規(guī)格:
  • 來(lái)源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Aqp7; Aquaporin-7; AQP-7; Aquaglyceroporin-7
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Full length protein
  • 表達(dá)區(qū)域:
    1-303
  • 氨基酸序列
    MAPRSVLETIQSVLQKNMVREFLAEFLSTYVMMVFGLGSVAHMVLGENSGSYLGVNLGFGFGVTMGVHVAGGISGAHMNAAVTFTNCALGRMTWKKFPVYVLGQFLGSFSAAATTYLIFYGAINHFAGGDLLVTGSKATANIFATYLPEYMTLWRGFLDEAFVTGMLQLCLFAITDKKNSPALQGTEPLVIGILVTVLGVSLGMNSGYAINPSRDLPPRLFTFIAGWGKQVFRAGNNWWWVPVVAPLLGAYLGGIVYLGLIHPSIPQDPQRLENFTARDQKVTASYKNAASANISGSVPLEHF
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney.
  • 基因功能參考文獻(xiàn):
    1. AQP-7 and -9 showed differential staining pattern in different stages of mouse estrus cycle. AQP-7 and -9-mediated glycerol transport in tanycyte cells might be under hormonal control to use glycerol as a potential energy substrate during mouse estrus cycle. PMID: 27746040
    2. upregulation of AQP7 plays an important role in improving of tolerance to hyperosmotic stress and survival of oocytes during cryopreservation by vitrification. PMID: 26634435
    3. AQP7 is expressed in human and mouse oocytes and upregulated by cryoprotectants. PMID: 23290745
    4. The over-expression of AQP7 contributes to improve insulin resistance in adipocytes, which is potentially correlated with the increased phosphorylation of PKB. PMID: 22877989
    5. Xenopus oocytes microinjected with either AQP7 or AQP9 cRNA (cloned from mouse adipocyte and rat liver, respectively) exhibited a 10-fold increase in arsenite permeability, indicating that both aquaglyceroporins recognize and transport arsenite. PMID: 11972053
    6. AQP7 may, directly or indirectly, play a role at a distal site in the exocytotic pathway. PMID: 22415076
    7. AQP7 in skin dendritic cells is primarily involved in antigen uptake and in the subsequent migration of them and is responsible for antigen presentation and the promotion of downstream immune responses. PMID: 21968069
    8. CM-chitin exerts anti-adipogenic effect on lipid accumulation through modulations of AMPK and aquaporin-7 signal pathways. PMID: 20573496
    9. Aquaporin 7 expansion during uterine decidualization is associated with elevated uterine glycerol accumulation and glycerol kinase expression. PMID: 21130427
    10. Coordinated regulation of fat-specific and liver-specific glycerol channels, aquaporin adipose and aquaporin 9. PMID: 12351427
    11. Epinephrine-stimulated glycerol secretion was also impaired in Aqp7 knockdown adipocytes PMID: 15591341
    12. adipocyte hypertrophy in AQP7 deficiency results from defective glycerol exit PMID: 15746100
    13. study clearly identified some physiological roles of AQP7 in the kidney; although AQP7 plays a minor role in water transport, AQP7 constitutes a major glycerol-reabsorbing pathway in the kidney PMID: 15998844
    14. AQP7 disruption elevates adipose glycerol kinase activity, accelerates triglycerides synthesis in adipocytes, and, finally, develops obesity. PMID: 16009937
    15. AQP7 is an important structural element in the choroid plexus and is possibly involved in the production of cerebrospinal fluid during brain development in mice PMID: 17052846
    16. AQP7 is expressed in capillary endothelia of adipose tissue (and cardiac and striated muscle) and is upregulated in white adipose tissue in response to streptozotocin-induced diabetes mellitus supporting its role in glycerol metabolism. PMID: 17077387
    17. analysis of the role of AQP7 in the testis and sperm using AQP7 knockout mice; male AQP7 knockout mice were not sterile, and their sperm did not show any morphologic or functional abnormalities PMID: 17123523
    18. Lowered gene expression of adipose triglyceride lipase and aquaglyceroporin 7 in peroxisome proliferator-activated receptor alpha null mice is not limiting for adipose triglyceride breakdown in vivo during fasting PMID: 17245390
    19. Data show that pancreatic beta cells express aquaporin 7, which appears to be a key regulator of intraislet glycerol content as well as insulin production and secretion. PMID: 17576812
    20. Both water influx and efflux occurred faster in Aqp7(-/-) sperm than wild-type. PMID: 18829704
    21. Follicles that were healthy but did not form an antrum or produce appropriate levels of steroids, however, demonstrated increasing levels of Star, Aqp7, Aqp8, and Hif1a and a 15-fold increase in Cyp19a1 at Day 8 of culture. PMID: 19005169
    22. AQP7 acts as a glycerol facilitator in cardiomyocytes and that glycerol is a substrate for cardiac energy production. PMID: 19297367

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein. Cytoplasm, cell cortex. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Lipid droplet.
  • 蛋白家族:
    MIP/aquaporin (TC 1.A.8) family
  • 組織特異性:
    Detected in proximal tubules in kidney. Detected in the capillary network between muscle fibers in skeletal muscle and heart, and in spermatids and on spermatozoa tails in testis and epididymis. Detected in white and brown adipose tissue, especially on sm
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 久久久久久人妻精品一区 | 少妇荡乳情欲办公室456视频| 中文日韩亚洲欧美制服| 欧美一区二区三区视频在线观看| 亚洲 日本 欧美 中文字幕| 任我橹这里只有精品 在线视频| 亚洲国产成人第一天堂| 性色做爰片在线观看ww | 久久综合亚洲色hezyo社区| 国产精品美女久久久久久2018| 久久亚洲人成综合网| 日日摸日日碰夜夜爽亚洲综合| a毛片终身免费观看网站| 欧美性白人极品hd| 海角社区在线视频播放观看 | 欧洲美女黑人粗性暴交视频| 女人夜夜春高潮爽a∨片传媒 | 久久一本人碰碰人碰| 日本老妇人乱xxy| 久久精品免视看国产成人| 欧美精品v欧洲精品| 上司人妻互换中文字幕| 97免费人妻无码视频| 亚洲精品制服丝袜四区| 亚洲精品国偷自产在线99人热 | 麻麻张开腿让我爽了一夜| 欧洲精品欧美精品| 日本丰满护士爆乳xxxx| 亚洲日韩一区精品射精| 18禁网站免费无遮挡无码中文| 在线人人车操人人看视频| 亚洲不卡一卡2卡三卡4卡5卡| 欧美三级a做爰在线观看| 国产影片中文字幕| 日韩av一国产av一中文字慕| 欧洲国产精品无码专区影院| 亚洲人成亚洲人成在线观看| 国产乱子伦视频在线播放| 乱码精品一区二区三区| 成人区人妻精品一区二区三区| 中文字幕日本最新乱码视频 |