在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Transmembrane protein 88 (TMEM88)

  • 中文名稱:
    人TMEM88重組蛋白
  • 貨號:
    CSB-CF023892HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    TMEM88
  • Uniprot No.:
  • 別名:
    TMEM88; TMEM88A; Transmembrane protein 88
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-159
  • 氨基酸序列
    MADVPGAQRAVPGDGPEPRDPLDCWACAVLVTAQNLLVAAFNLLLLVLVLGTILLPAVTM LGFGFLCHSQFLRSQAPPCTAHLRDPGFTALLVTGFLLLVPLLVLALASYRRLCLRLRLA DCLVPYSRALYRRRRAPQPRQIRASPGSQAVPTSGKVWV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development.
  • 基因功能參考文獻:
    1. TMEM88 inhibits the TGF-beta1-stimulated cell proliferation, migration and extracellular matrix expression in keloid fibroblasts. PMID: 28946191
    2. TMEM88, CCL14, and CLEC3B genes were stable and available in predicting the survival and palindromia time of hepatocellular carcinoma. These genes could function as potential prognostic genes contributing to improve patients' outcomes and survival PMID: 28718365
    3. Results support that OC platinum resistance was correlated with TMEM88 overexpression regulated through decreased promoter methylation. Data suggest that TMEM88 functions as an inhibitor of Wnt signaling, contributing to the development of platinum resistance. PMID: 27374141
    4. TMEM88 stimulated triple negative breast cancer cell invasion by interacting with DVL1. PMID: 26325443
    5. mislocalization of TMEM88 to the cytosol in non-small cell lung cancer cells ablates its Wnt pathway regulatory properties, thereby promoting invasion and metastasis by activating the p38-GSK3beta-Snail signaling pathway. PMID: 26359454
    6. TMEM88 is crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte. PMID: 23924634
    7. miRNA-708 acts as an oncogene contributing to tumor growth and disease progression by directly downregulating TMEM88 PMID: 22573352
    8. TMEM88 associates with Dvl proteins and regulates Wnt signaling in a context-dependent manner PMID: 21044957

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    TMEM88 family
  • 數據庫鏈接:

    HGNC: 32371

    OMIM: 617813

    KEGG: hsa:92162

    STRING: 9606.ENSP00000301599

    UniGene: Hs.389669



主站蜘蛛池模板: 欧美最猛黑人xxxx| 亚洲中文色欧另类欧美| 国产95在线 | 欧美| 久久精品无码一区二区app| 中文字幕无码专区人妻系列| 国产成人高清亚洲一区妲妃| 纯爱无遮挡h肉动漫在线播放| 国产精品毛片无码| 理论片87福利理论电影| 无码av片av片av无码| 免费两性的视频网站| 亚洲乱码中文字幕综合234| 婷婷丁香五月缴情视频| 东京无码熟妇人妻av在线网址| 国产精品久久久久9999小说| 成人精品一区二区三区电影免费 | 97国产超碰一区二区三区| 国产亚洲久久久久久久| 亚瑟国产精品久久| 亚洲精品成人无码中文毛片不卡 | 狠狠躁夜夜躁人人爽天天| 人妻少妇精品视中文字幕国语| 日本乱码伦午夜福利在线| 欧洲乱码伦视频免费| 伊人狠狠色丁香婷婷综合| 日本亚洲欧美高清专区vr专区 | 免费看成人aa片无码视频| 欧美xxxxx在线观看| 国产无遮挡a片无码免费软件| 无码aⅴ精品一区二区三区浪潮| 人人妻人人藻人人爽欧美一区 | 久热国产vs视频在线观看| 亚洲日产韩国一二三四区| 97夜夜澡人人爽人人模人人喊| 亚洲欧美日韩精品久久| 熟妇人妻无码中文字幕老熟妇| 国产美女a做受大片观看| 国产成av人片在线观看无码| 中文字幕一区二区三区精彩视频| 久久婷婷久久一区二区三区| 天堂岛国av无码免费无禁网站 |