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Recombinant Human Transmembrane protein 45B (TMEM45B)

  • 中文名稱:
    人TMEM45B重組蛋白
  • 貨號:
    CSB-CF023843HU
  • 說明書:
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    TMEM45B
  • Uniprot No.:
  • 別名:
    TMEM45B; Transmembrane protein 45B
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-275
  • 氨基酸序列
    MANFKGHALPGSFFLIIGLCWSVKYPLKYFSHTRKNSPLHYYQRLEIVEAAIRTLFSVTG ILAEQFVPDGPHLHLYHENHWIKLMNWQHSTMYLFFAVSGIVDMLTYLVSHVPLGVDRLV MAVAVFMEGFLFYYHVHNRPPLDQHIHSLLLYALFGGCVSISLEVIFRDHIVLELFRTSL IILQGTWFWQIGFVLFPPFGTPEWDQKDDANLMFITMCFCWHYLAALSIVAVNYSLVYCL LTRMKRHGRGEIIGIQKLNSDDTYQTALLSGSDEE
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. TMEM45B may be a new potent therapeutic molecule for the treatment of gastric cancer. PMID: 29803169
    2. TMEM45B plays an important role in regulating the proliferation, migration, and invasion of osteosarcoma cells. PMID: 28244852
    3. TMEM45B expression was significantly upregulated in pancreatic cancer tissues and cell lines. Moreover, TMEM45B was significantly positively correlated with the cell cycle and metastasis up pathways and regulated expression of proteins involved. This indicates an important role of TMEM45B in pancreatic cancer carcinogenesis. PMID: 27108650
    4. Data show that transmembrane protein 45B (TMEM45B) was overexpressed in lung cancer and its expression correlated with overall survival of patients. PMID: 27225290
  • 亞細胞定位:
    Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    TMEM45 family
  • 數據庫鏈接:

    HGNC: 25194

    KEGG: hsa:120224

    STRING: 9606.ENSP00000281441

    UniGene: Hs.504301



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