在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human T cell receptor beta constant 1 (TRBC1), partial

  • 中文名稱:
    人TRBC1重組蛋白
  • 貨號:
    CSB-CF024291HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    TRBC1; T cell receptor beta constant 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 表達區域:
    1-177
  • 氨基酸序列
    EDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFFPDHVELSWWVNGKEVHSGVSTDP QPLKEQPALNDSRYCLSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQI VSAEAWGRADCGFTSVSYQQGVLSATILYEILLGKATLYAVLVSALVLMAMVKRKDF
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    10xHis-SUMO-tag
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens. Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn, ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation. The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity.
  • 亞細胞定位:
    Cell membrane.
  • 數據庫鏈接:

    HGNC: 12156

    OMIM: 186930

    UniGene: Hs.382212



主站蜘蛛池模板: 国产精品久久久久9999赢消| 麻豆av久久av盛宴av| 中文字幕无码乱码人妻系列蜜桃 | 熟睡人妻被讨厌的公侵犯深田咏美| 在线观看日本亚洲一区| 色综合天天综合欧美综合| 亚洲国产成人精品无码区蜜柚| 99偷拍视频精品一区二区 | 婷婷五月综合色中文字幕| 日日碰狠狠躁久久躁婷婷| 欧美牲交a欧美牲交aⅴ免费下载| 国产情侣激情在线视频| 成人乱码一区二区三区av66| 啦啦啦www在线观看免费视频 | 亚洲国产人成自精在线尤物| 最近2019中文字幕在线| 99久久国产综合精品成人影院| 中文字幕人成无码人妻 | 国产区图片区小说区亚洲区| 亚洲第一狼人天堂久久| 国产乱子伦在线一区二区| 精品无码国产一区二区三区51安| 久久久不卡国产精品一区二区| 午夜av亚洲一码二中文字幕青青 | 国产情侣真实露脸在线| 国产情侣草莓视频在线| 亚洲国产av导航第一福利网| 人妻少妇精品久久久久久| yyyy11111少妇无码影院| 丰满人妻被黑人中出849| 成人精品天堂一区二区三区| 精品人妻少妇一区二区三区不卡| 无套内谢少妇毛片aaaa片免费| 久久国产亚洲精品无码| 乱妇乱女熟妇熟女网站| 国产mv在线天堂mv免费观看| 午夜性刺激在线视频免费| 天堂www中文在线资源| 自拍偷在线精品自拍偷99| 久久久久人妻精品区一三寸| 无码人妻丝袜在线视频|