在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Platelet glycoprotein IX (GP9)

  • 中文名稱:
    人GP9重組蛋白
  • 貨號:
    CSB-CF009690HU
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    GP9; Platelet glycoprotein IX; GP-IX; GPIX; Glycoprotein 9; CD antigen CD42a
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區(qū)域:
    17-177
  • 氨基酸序列
    TKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAAHGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
  • 基因功能參考文獻:
    1. Case Report: suggest that alloantibodies directed against Cab4b, the first human platelet antigen carried by glycoprotein IX, can induce severe neonatal thrombocytopenia. PMID: 28561420
    2. factor XI is localized to GPIb in membrane rafts and this association is important for promoting the activation of factor XI by thrombin on the platelet surface PMID: 12517745
    3. Raft association and cytoskeletal linkage of the platelet GPIb-IX-V complex are interrelated and are required for optimal receptor function, by attracting signaling proteins and membrane skeletal association allows proteins to move to new locations. PMID: 19874464
    4. the putative convex surface of the LRR domain in GPIX is sufficient, in the context of full-length subunit, to mediate its association with GPIbbeta PMID: 19566547
    5. Novel nonsense mutation is associated with Bernard-Soulier syndrome. PMID: 12447957
    6. findings indicate that the Ala14-->Thr mutation in the transmembrane region of GP IX does not induce intracellular GP Ib/IX complex degradation, but prevents its insertion in the cytoplasmic membrane of platelets and CHO cells PMID: 15351858
    7. the first non-Caucasian Turkish Bernard-Soulier syndrome case due to GPIX N45S and is likely the result of a recurrent mutational event. PMID: 17804902
    8. Findings point to a role of the GPIb-V-IX complex intrinsic to megakaryocytes at the stage of proplatelet formation and suggest a functional link with the underlying microtubular cytoskeleton in platelet biogenesis. PMID: 19377075
    9. Homozygous missense mutation in position 1829 (A(R)G) of the GPIX gene causes Bernard-Soulier syndrome in a Swiss family. PMID: 19404517

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Bernard-Soulier syndrome (BSS)
  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4444

    OMIM: 173515

    KEGG: hsa:2815

    STRING: 9606.ENSP00000303942

    UniGene: Hs.1144



主站蜘蛛池模板: 精品少妇爆乳无码av无码专区| 人妻av中文系列| 黑人巨茎美女高潮视频| 国产最新进精品视频| 强伦人妻一区二区三区视频18| 国产精品美女乱子伦高| 亚洲人成网站18禁止人| 免费一区二区三区成人免费视频| 国精品人妻无码一区二区三区性色| 无码av高潮喷水无码专区线| 国产免费观看久久黄av片| 又粗又硬又大又爽免费视频播放 | 亚洲日韩乱码久久久久久| 免费观看又色又爽又黄的韩国| 午夜影视啪啪免费体验区入口| 熟妇丰满大屁股在线播放| 亚洲人成电影在线天堂色 | 久久精品人妻无码一区二区三区v 国产薄丝脚交视频在线观看 | 亚洲综合久久精品无码色欲| 国产suv精二区| 色婷婷av一区二区三区浪潮| 亚洲色丰满少妇高潮18p| 对白脏话肉麻粗话av| 狠狠色噜噜狠狠狠狠av不卡| 99999久久久久久亚洲| 久久久久无码精品国产| 色五月激情五月| 自慰系列无码专区| 亚洲精品国产品国语原创| 国产真实露脸乱子伦| 久久久国产精品黄毛片| 国产手机在线精品| 欧美成人va免费看视频| 噜噜噜av久久| 国产老妇伦国产熟女老妇高清| 青草青草久热精品视频在线观看| 狠狠做深爱婷婷丁香综合| 无码人妻一区二区三区免费n鬼逝| 草草浮力地址线路①屁屁影院| 国产999精品久久久久久| 九个美女露脸撒尿嘘嘘视频|