在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Palmitoyltransferase ZDHHC7 (ZDHHC7)

  • 中文名稱:
    人ZDHHC7重組蛋白
  • 貨號:
    CSB-CF889140HU
  • 說明書:
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
    ZDHHC7
  • Uniprot No.:
  • 別名:
    ZDHHC7; Palmitoyltransferase ZDHHC7; Acyltransferase ZDHHC7; Zinc finger DHHC domain-containing protein 7; DHHC-7
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-308
  • 氨基酸序列
    MQPSGHRLRDVEHHPLLAENDNYDSSSSSSSEADVADRVWFIRDGCGMICAVMTWLLVAY ADFVVTFVMLLPSKDFWYSVVNGVIFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMES LQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTM YIALSSVHALILCGFQFISCVRGQWTECSDFSPPITVILLIFLCLEGLLFFTFTAVMFGT QIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRFRRLPTRPR KGGPEFSV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane and their function in rapid intracellular signaling upon binding of sex hormones. Palmitoylates GNAQ, a heterotrimeric G protein, regulating its dynamic localization at the plasma membrane and is thereby involved in GNAQ-dependent G protein-coupled receptor signaling pathways. Functions also in ligand-induced cell death by regulating the FAS signaling pathway through the palmitoylation and stabilization of the receptor at the plasma membrane. In epithelial cells, palmitoylates SCRIB and regulates its localization to the plasma membrane, regulating indirectly cell polarity and differentiation. Also palmitoylates JAM3 and promotes its expression at tight junctions and regulates its function in cell migration. Palmitoylates the glucose transporter GLUT4/SLC2A4 and controls the insulin-dependent translocation of GLUT4 to the plasma membrane. In brain, could also palmitoylate SNAP25 and DLG4/PSD95. Could also palmitoylate DNAJC5 and regulate its localization to the Golgi membrane. Could also palmitoylate NCDN. May play a role in follicle stimulation hormone (FSH) activation of testicular Sertoli cells.
  • 基因功能參考文獻(xiàn):
    1. identified DHHC7 as a JAM-C palmitoylating enzyme PMID: 28196865
    2. The ZDHHC7-mediated SCRIB palmitoylation is critical for SCRIB membrane targeting, cell polarity and tumor suppression, providing new mechanistic insights of how dynamic protein palmitoylation regulates cell polarity and tumorigenesis. PMID: 27380321
    3. DHHC7-mediated palmitoylation of Fas allows a proper Fas expression level by preventing its degradation through the lysosomes. PMID: 25301068
    4. the DHHC-7 and -21 proteins are novel targets to selectively inhibit membrane sex steroid receptor localization and function PMID: 22031296
  • 亞細(xì)胞定位:
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族:
    DHHC palmitoyltransferase family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 18459

    OMIM: 614604

    KEGG: hsa:55625

    UniGene: Hs.461610



主站蜘蛛池模板: 国产精品久久久| 亚洲国产成在人网站天堂| 亚洲va无码va在线va天堂| 亚洲综合无码一区二区三区不卡| 免费人成视频在线播放视频| 国产日产精品一区二区三区四区的特点 | 久久精品免视看国产成人| 狠狠色色综合站| 精品综合久久久久久98| 色悠久久久久久久综合网伊人 | 午夜福制92视频| 人妻体验按摩到忍不住哀求继续| 无码毛片视频一区二区本码| 国产精品丝袜久久久久久不卡| 日日噜噜大屁股熟妇| 男女猛烈无遮挡免费视频在线观看| 真实国产老熟女无套中出| 久久www免费人成精品| 碰超免费人妻中文字幕| 香蕉eeww99国产精选免费| 性做久久久久久久| 四虎永久在线精品无码视频| 日本特黄aaaaaa片在线观看| 日本大片免费观看视频| 国语自产偷拍精品视频偷| 青青国产线免观| 国产精品美脚玉足脚交| 大尺度无遮挡激烈床震网站 | 国产区又黄又硬高潮的视频| 在线天堂资源www中文| 久久久久黑人强伦姧人妻| 永久免费观看美女裸体的网站| 国产系列丝袜熟女精品网站| 日本熟妇中文字幕三级| 亚洲国产成人久久综合一区| 久久综合给合久久狠狠狠97色69| 国产亚洲人成网站观看| 亚洲熟妇无码av不卡在线播放| 国产成人午夜高潮毛片| 亚洲精品55夜色66夜色| 精品精品国产理论在线观看|