在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Heparan-sulfate 6-O-sulfotransferase 1 (HS6ST1)

  • 中文名稱:
    人HS6ST1重組蛋白
  • 貨號:
    CSB-CF010756HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    HS6ST1
  • Uniprot No.:
  • 別名:
    HS6ST1; HS6ST; Heparan-sulfate 6-O-sulfotransferase 1; HS6ST-1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-411
  • 氨基酸序列
    MRRRRAGGRTMVERASKFVLVVAGSVCFMLILYQYAGPGLSLGAPGGRAPPDDLDLFPTPDPHYEKKYYFPVRELERSLRFDMKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLDRRDSAALRTPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNLSFIPEGKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNSTRAGGVEVDEDTIRRIEELNDLDMQLYDYAKDLFQQRYQYKRQLERREQRLRSREERLLHRAKEALPREDADEPGRVPTEDYMSHIIEKW
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid.
  • 基因功能參考文獻:
    1. RT-PCR analysis showed that the overall transcriptional activity of the main Heparan Sulfate biosynthesis-involved genes (EXT1, EXT2, NDST1, NDST2, GLCE, HS2ST1, HS3ST1, HS3ST2, HS6ST1, HS6ST2, SULF1, SULF2, HPSE) was decreased by 1.5-2-fold in Grade II-III glioma. PMID: 29104277
    2. HS6ST-1 and HS6ST-2 have roles in regulating the angiogenic program in ovarian cancer cells affecting HB-EGF signaling and subsequent expression of angiogenic cytokines by cancer cells PMID: 24563483
    3. Hs6st1 and Hs2st generate conditions conducive to corpus callosum development. PMID: 24501377
    4. idiopathic hypogonadotrophic hypogonadism--associated HS6ST1 mutations display reduced activity in vitro and in vivo, suggesting that HS6ST1 and the complex modifications of extracellular sugars are critical for normal development PMID: 21700882
    5. we have characterized HS6ST-2 and HS6ST-1 human isologues, including their chromosomal localizations,HS6STs could also transfer sulphate to N -sulphoglucosamine residues located at the non-reducing terminal of HS with high affinity. PMID: 12492399

    顯示更多

    收起更多

  • 相關疾病:
    Hypogonadotropic hypogonadism 15 with or without anosmia (HH15)
  • 亞細胞定位:
    Membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Sulfotransferase 6 family
  • 組織特異性:
    Expressed in fetal brain.
  • 數據庫鏈接:

    HGNC: 5201

    OMIM: 604846

    KEGG: hsa:9394

    STRING: 9606.ENSP00000259241

    UniGene: Hs.512841



主站蜘蛛池模板: 亚洲精品一区二区三区婷婷月| 国产午夜精品久久精品电影| 97国产精东麻豆人妻电影| 欧美人与动牲交zooz男人| 亚洲欧美日韩中字视频三区| 亚洲婷婷五月激情综合app| 国产精品人妻熟女男人的天堂| 青青草免费公开视频| 狠狠97人人婷婷五月| 小sao货水好多真紧h无码视频 | 激情影院内射美女| 丁香花在线影院观看在线播放 | 18禁无遮挡啪啪无码网站| 无码h肉动漫在线观看| 性久久久久久| 偷看农村妇女牲交| 天堂在线www资源在线| 野外少妇激情aa 级视频| 无码任你躁久久久久久| 国产精品兄妹在线观看麻豆| 精品人妻少妇嫩草av无码专区 | 国产一区二区三精品久久久无广告| 中国内地毛片免费高清| 玩弄人妻少妇500系列视频| 在线亚洲综合欧美网站首页| 亚洲精品无码中文久久字幕| 亚洲熟女综合色一区二区三区 | 国产一起色一起爱| 无码少妇一区二区| 久久九九久精品国产| 好日子在线观看视频大全免费动漫| 最新 国产 精品 精品 视频| 成人美女黄网站色大免费的| 中文字幕无码不卡一区二区三区| 99久久久无码国产精品动漫| 精品一卡2卡三卡4卡乱码精品视频| 国产做爰xxxⅹ久久久精华液| 日韩超碰人人爽人人做人人添| 色欲久久人妻内射| 自偷自拍亚洲综合精品麻豆| 国产做爰xxxⅹ久久久精华液|