在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Heme transporter HRG1 (SLC48A1)

  • 中文名稱:
    人SLC48A1重組蛋白
  • 貨號(hào):
    CSB-CF740701HU
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
    SLC48A1
  • Uniprot No.:
  • 別名:
    SLC48A1; HRG1; Heme transporter HRG1; Heme-responsive gene 1 protein homolog; HRG-1; hHRG-1; Solute carrier family 48 member 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-146
  • 氨基酸序列
    MAPSRLQLGLRAAYSGISSVAGFSIFLVWTVVYRQPGTAAMGGLAGVLALWVLVTHVMYM QDYWRTWLKGLRGFFFVGVLFSAVSIAAFCTFLVLAITRHQSLTDPTSYYLSSVWSFISF KWAFLLSLYAHRYRADFADISILSDF
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
  • 基因功能參考文獻(xiàn):
    1. HRG-1 may represent a novel target for selectively disrupting V-ATPase activity and the metastatic potential of cancer cells. PMID: 24141772
    2. These results reveal HRG1 as the long-sought heme transporter for heme-iron recycling in macrophages and suggest that genetic variations in HRG1 could be modifiers of human iron metabolism. PMID: 23395172
    3. a model in which heme is translocated across membranes facilitated by conserved amino acids positioned on the exoplasmic, cytoplasmic, and transmembrane regions of HRG-1-related proteins. PMID: 22174408
    4. SLC48A1 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    5. HRG-1 regulates V-ATPase activity, which is essential for endosomal acidification, heme binding, and receptor trafficking in mammalian cells. PMID: 19875448
    6. Human and worm proteins localize together, and bind and transport haem, thus establishing an evolutionarily conserved function for HRG-1. PMID: 18418376

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    HRG family
  • 組織特異性:
    Highly expressed in the brain, kidney, heart and skeletal muscle. Moderately expressed in the liver, lung, placenta and small intestine.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 26035

    OMIM: 612187

    KEGG: hsa:55652

    UniGene: Hs.438867



主站蜘蛛池模板: 国产精品久久久久久妇女6080| av中文字幕无码免费看| 午夜精品乱人伦小说区 | 亚洲国产成人精品无码区99| 久久成人国产精品免费| 午夜无码片在线观看影院y| 羞羞影院午夜男女爽爽免费| 久久丫精品久久丫| 色综合久久中文娱乐网| 色一情一乱一乱一区99av| 农村乱人伦一区二区| 抽插丰满内射高潮视频| 精品无码久久久久国产动漫3d| 欧美另类又黄又爽的a片| 性高朝久久久久久久久久| 97色伦图片97综合影院| 2021国产精品视频网站| 久久99精品久久久久久久不卡 | 国产精品无码一区二区牛牛| 性一交一乱一乱一视频 | 久久人妻无码中文字幕第一 | 国产成人综合久久精品推最新| 国产亚洲人成无码网在线观看| 国产成人av一区二区三区不卡| 亚洲无av在线中文字幕| 亚洲日本中文字幕天天更新| 久久国产福利一区二区| 久久久97丨国产人妻熟女| 精品熟女少妇av免费观看| 免费人成在线观看网站品善网| 亚洲精品中文字幕久久久久下载| 农村老熟妇乱子伦视频| 国产毛a片啊久久久久久保和丸| 欧美肥婆性猛交xxxx| 中文字幕丝袜第1页| 亚洲成a人v影院色老汉影院| 美女把尿囗扒开让男人添| 亚洲欧美午夜理论电影在线观看| 韩日午夜在线资源一区二区| 亚洲综合精品伊人久久| 欧美人与动性xxxxbbbb|