在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Golgi integral membrane protein 4 (GOLIM4)

  • 中文名稱:
    人GOLIM4重組蛋白
  • 貨號:
    CSB-CF009665HU
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
    GOLIM4
  • Uniprot No.:
  • 別名:
    GOLIM4; GIMPC; GOLPH4; GPP130; Golgi integral membrane protein 4; Golgi integral membrane protein, cis; GIMPc; Golgi phosphoprotein 4; Golgi-localized phosphoprotein of 130 kDa; Golgi phosphoprotein of 130 kDa
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-696
  • 氨基酸序列
    MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQLQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi.
  • 基因功能參考文獻:
    1. Authors provide evidence that Mn-induced exit of GPP130 from the trans-Golgi network (TGN) toward lysosomes is mediated by the sorting receptor sortilin interacting with the lumenal stem domain of GPP130. PMID: 28768823
    2. Findings suggest the unexpected presence of quality control in the Golgi that recognizes aggregated Golgi proteins, GPP130, and targets them for degradation in lysosomes. PMID: 26446839
    3. Characteristics of GPP130 and its STx/STx1 binding interface. PMID: 23761068
    4. the stem domain of GPP130 is a novel Mn sensor in the Golgi lumen of mammalian cells PMID: 20130081
    5. both the translation and transcription are regulated independent of the cell cycle and dissociated from the duplication of the centrosome PMID: 12207053
    6. GPP130 mediates exit from endosomes and thereby underlies Shiga toxin invasion and retrieval-based targeting of other cycling Golgi proteines PMID: 15331763
    7. Multiple pH-regulated steps affect the trafficking of GPP130. PMID: 17605763

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Membrane; Lipid-anchor. Note=Localizes to cis and medial Golgi cisternae. Probably cycles between early Golgi and distal compartments like endosome.
  • 蛋白家族:
    GOLIM4 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 15448

    OMIM: 606805

    KEGG: hsa:27333

    STRING: 9606.ENSP00000417354

    UniGene: Hs.143600



主站蜘蛛池模板: 羞羞色男人的天堂| аⅴ资源中文在线天堂| 色妞www精品视频| 成 年 人 黄 色 大 片大 全| 久久久久欧美精品| 日日躁狠狠躁狠狠爱| 精品无码专区久久久水蜜桃| 免费1级做爰片在线观看爱| 午夜大片免费男女爽爽影院| 精品国产av无码一区二区三区| 三级在线看中文字幕完整版| 十八禁啪啪无遮挡网站| 精品无码国模私拍视频| 中文字幕无码免费久久| 成人av片无码免费网站| aa区一区二区三无码精片| 免费视频好湿好紧好大好爽| 少妇被又大又粗又爽毛片久久黑人| 亚洲香蕉成人av网站在线观看| 成人区精品一区二区婷婷| 4480yy私人精品国产| 黄瓜视频在线观看网址| 亚洲精品国产一区二区| 欧洲美熟女乱又伦免费视频| 国产女主播白浆在线看| www插插插无码免费视频网站| 人禽杂交18禁网站免费| 亚洲成在线aⅴ免费视频| 国产av无码专区亚汌a√| 久久狠狠高潮亚洲精品| 精品无码日韩一区二区三区不卡 | aaa欧美色吧激情视频| 一区一区三区产品乱码| 又黄又爽又无遮挡免费的网站 | 久久综合99re88久久爱| 乱码视频午夜间在线观看| 国产午夜精品无码| 18禁男女爽爽爽午夜网站免费| 亚洲国产成人久久综合三区| 国产成人欧美日韩在线电影| 少妇被躁爽到高潮无码人狍大战|