在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human G-protein coupled receptor 1 (GPR1)

  • 中文名稱:
    人GPR1重組蛋白
  • 貨號:
    CSB-CF009728HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    CMKLR2; GPR1; Chemerin-like receptor 2; Chemerin chemokine-like receptor 2; Chemokine-like receptor 2; G-protein coupled receptor 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-355
  • 氨基酸序列
    MEDLEETLFEEFENYSYDLDYYSLESDLEEKVQLGVVHWVSLVLYCLAFVLGIPGNAIVI WFTGFKWKKTVTTLWFLNLAIADFIFLLFLPLYISYVAMNFHWPFGIWLCKANSFTAQLN MFASVFFLTVISLDHYIHLIHPVLSHRHRTLKNSLIVIIFIWLLASLIGGPALYFRDTVE FNNHTLCYNNFQKHDPDLTLIRHHVLTWVKFIIGYLFPLLTMSICYLCLIFKVKKRSILI SSRHFWTILVVVVAFVVCWTPYHLFSIWELTIHHNSYSHHVMQAGIPLSTGLAFLNSCLN PILYVLISKKFQARFRSSVAEILKYTLWEVSCSGTVSEQLRNSETKNLCLLETAQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too. Acts also as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway.; (Microbial infection) Coreceptor for HIV-1.
  • 基因功能參考文獻:
    1. CMKLR1 and GPR1 were widely expressed in vascular smooth muscle. PMID: 27742615
    2. The Gene-based analyses revealed four significant associations in the WT1, ZC3H12C, DLGAP2, and GPR1 genes at p < 0.05. in this study. PMID: 25391383
    3. GPR1 gene is imprinted and paternally expressed in human and mouse. PMID: 20385583
    4. identified homologous amino acid sequences in amino-terminal regions between CCR5 and GPR1/ sequences are important for G protein-coupled receptors to make the conformation critical for the interaction with the Env protein of HIV-1. PMID: 20334567
    5. GPR1 is a senescence-associated gene in normal human oral keratinocytes. PMID: 12837283
    6. Data report that a synthetic peptide derived from the NH2-terminal extracellular region of an orphan GPCR, GPR1, inhibited infection of not only an HIV-1 variant that uses GPR1 as a co-receptor, but also X4, R5, and R5X4 viruses. PMID: 15919664

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Expressed in hippocampus.
  • 數據庫鏈接:

    HGNC: 4463

    OMIM: 600239

    KEGG: hsa:2825

    STRING: 9606.ENSP00000384345

    UniGene: Hs.184907



主站蜘蛛池模板: 国产欧美日本亚洲精品一5区| 大学生被内谢粉嫩无套| 少妇spa推油被扣高潮| 国产综合一区二区三区黄页秋霞| 亚洲国产精品美女久久久久| 国产欧美熟妇另类久久久| 麻豆高清免费国产一区| 国产色产综合色产在线视频| 无码国产一区二区三区四区| 久久99精品国产免费观观| 青青草大香焦在线综合视频 | 久久亚洲精精品中文字幕| 国产偷抇久久精品a片69| 亚洲精品成人网站在线播放| 精品无码久久久久国产app| 久久棈精品久久久久久噜噜 | 日本在线看片免费人成视频| 成人网站精品久久久久| 顶级欧美做受xxx000| 99久久99久久精品免费看蜜桃| 丰满岳乱妇一区二区三区| 久久人妻国产精品| 日韩人妻ol丝袜av一二区| 成人性生交大片免费看视频app| 深夜国产一区二区三区在线看| 77se77亚洲欧美在线| 国产真人做爰视频免费| 久久精品国产99久久久古代| 国产色在线 | 国产| 欧美成 人 在线播放视频 | 欧美mv日韩mv国产网站| 少妇放荡的呻吟干柴烈火动漫| 果冻传媒2021精品一区| 国产在线视频一区二区三区98| 免费久久99精品国产自在现线| 久久久综合九色综合88| 久久久久久久久久久免费精品| 中文字幕 人妻熟女| 亚洲精品一区二区三区婷婷月| 人人揉揉揉香蕉大免费| 色综合久久久无码中文字幕波多 |