在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Guinea pig Potassium channel subfamily K member 1 (KCNK1)

  • 中文名稱:
    Recombinant Guinea pig Potassium channel subfamily K member 1(KCNK1)
  • 貨號:
    CSB-CF848125GU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    KCNK1
  • Uniprot No.:
  • 別名:
    KCNK1; Potassium channel subfamily K member 1; Inward rectifying potassium channel protein TWIK-1
  • 種屬:
    Cavia porcellus (Guinea pig)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-336
  • 氨基酸序列
    MLQSLAGSSCVRLVERHRSAWCFGLLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLK RRFLEEHECLSEPQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGY GHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQMVG IVHAVVLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQK FRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIVEHDQLS FSSITDQAASVKEEQKQSEPFVAAQVSAYAEDSASH
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium channel activity, when expressed in heterologous systems, and can function as weakly inward rectifying potassium channel. Channel activity is modulated by activation of serotonin receptors. Heterodimeric channels containing KCNK1 and KCNK2 have much higher activity, and may represent the predominant form in astrocytes. Heterodimeric channels containing KCNK1 and KCNK3 or KCNK9 have much higher activity. Heterodimeric channels formed by KCNK1 and KCNK9 may contribute to halothane-sensitive currents. Mediates outward rectifying potassium currents in dentate gyrus granule cells and contributes to the regulation of their resting membrane potential. Contributes to the regulation of action potential firing in dentate gyrus granule cells and down-regulates their intrinsic excitability. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled receptors, such as F2R and CNR1. Required for normal ion and water transport in the kidney. Contributes to the regulation of the resting membrane potential of pancreatic beta cells. The low channel activity of homodimeric KCNK1 may be due to sumoylation. The low channel activity may be due to rapid internalization from the cell membrane and retention in recycling endosomes.
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Recycling endosome. Cell junction, synapse, synaptic cell membrane. Cytoplasmic vesicle. Perikaryon. Cell projection, dendrite. Cell projection. Apical cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Two pore domain potassium channel (TC 1.A.1.8) family
  • 數據庫鏈接:


主站蜘蛛池模板: 人人插人人插人人爽| 中文字幕日产乱码国内自| 亚洲国产欧美在线人成最新| 日本精品人妻无码77777| 高潮又爽又无遮挡又免费| 无码一区二区三区老色鬼| 亚洲成a人片在线观看的电影| 玩两个丰满老熟女| 人人妻人人澡人人爽人人精品av| 18禁黄网站禁片免费观看国产| 精品999日本久久久影院| 亚洲精品久久久口爆吞精| 国产对白老熟女正在播放| 特级无码毛片免费视频| 99re6热精品视频在线观看| 亚洲国产制服丝袜先锋| 真人作爱90分钟免费看视频| 俺也来俺也去俺也射| 亚洲人成精品久久久久桥| 久久精品国产久精国产果冻传媒| 先锋影音av最新资源网| 婷婷五月综合激情| 亚洲最大的成人网站| 欧美亚洲色欲色一欲www| 超薄肉色丝袜一区二区| 97人妻精品一区二区三区| 亚洲国内精品自在线影院| 成人性无码专区免费视频| 欧美日韩亚洲精品瑜伽裤| 麻豆果冻传媒精品| 日韩精品一区二区三区在线观看l| 骚虎成人免费99xx| 欧美日本韩国亚洲| 福利视频在线播放| 最近日本mv字幕免费高清完整版 | 国产精品熟女高潮视频| 亚洲精品久久久无码av片软件| 嫩草国产福利视频一区二区| 国产精品盗摄!偷窥盗摄| 久久人妻无码中文字幕| 亚洲精品无码乱码成人|