在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Dog Cyclic nucleotide-gated cation channel beta-3 (CNGB3)

  • 中文名稱:
    Recombinant Dog Cyclic nucleotide-gated cation channel beta-3(CNGB3)
  • 貨號:
    CSB-CF850746DO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    CNGB3; Cyclic nucleotide-gated cation channel beta-3; Cone photoreceptor cGMP-gated channel subunit beta; Cyclic nucleotide-gated cation channel modulatory subunit; Cyclic nucleotide-gated channel beta-3; CNG channel beta-3
  • 種屬:
    Canis familiaris (Dog) (Canis lupus familiaris)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-782
  • 氨基酸序列
    MFKSLTIKSNKVKPREENDENKQDPDPSNQPQQSTRQGENKSENKSLQTKMTPVTFEESH AKMQDKISEKNSLRDLTTNPNHQHPTESKGAMSEQKEMETGKEGLVSPKSKPLGVPVINE YADAQLHNLVRRMRQRTMLYKKKLAEGDISSPEASPQTAKPTAVPSTQESNAKLKEEHYY HILCFKFQKMPLTEYLKRFRLPGSIDSYTDRLYLLWLLLVTIAYNWNCWLIPLRLVFPYQ TPDNTHYWFITDITCDIIYLCDMLLIQPRLQFIKGGDIMVDSNELKRHYRSSTKFQLDVA SVMPFDVFYLFFGFNPVFRMNRILKYTSFFEFNHHLESIMDKAYIYRVIRTTGYLLYTLH INACIYYWASDYEGIGSTKWVYNGEGNKYLRCYYWAVRTLITIGGLPEPQTSFEIVFQLL NFFSGVFVFSSLIGQMQDVIGAATANQNNFRISMDHTISYMNTYSIPKNVQNRVRTWYEY TWDSQRMLDESDLLCTLPVTMQLALTVDVNLSIISKVELFKGCDTQMIYDMLLRLKSTVY LPGDFVCKKGEIGKEMYIIKQGEVQVLGGSDGAQVLVTLKAGAVFGEISLLAGRGGNRRT ANVIAHGFANLLTLDKKTLQEILVHYPDSEKLLMKKASVLLKKKAPATETTPPRKGLAFL FPPKQETPKIFKALLGGTGKAGLTRLLKLKREQTIQKTSENSEEGGGKRREYEDKEREPS EKILDSSECRANCIIAEEMPQSIRRAALPRGTTRQSLIISMAPSAEAGEEVLTIEVKEKA KQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
  • 基因功能參考文獻:
    1. Missense mutation at position 262 in the canine CNGB3 (D262N) subunit results in loss of cone function (daylight blindness), suggesting an important role for this aspartic acid residue in channel biogenesis. PMID: 24586388
    2. Day blindness shows genetic heterogeneity within the CNGB3 gene of the Alaskan Malamute population of Australia. PMID: 16879359
  • 相關疾病:
    Defects in CNGB3 are a cause of cone degeneration (cd). Cd is characterized by day-blindness and absence of retinal cone function. This autosomal recessive disorder occurs naturally in the Alaskan Malamute and German Shorthaired Pointer breeds.
  • 亞細胞定位:
    Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Cyclic nucleotide-gated cation channel (TC 1.A.1.5) family, CNGB3 subfamily
  • 數據庫鏈接:

    KEGG: cfa:403554

    STRING: 9615.ENSCAFP00000036190

    UniGene: Cfa.72



主站蜘蛛池模板: 国产精品亚洲一区二区无码| 国产精品久久久久久久久久久免费看 | 国产精品99久久久久久www| 欧美日韩不卡视频合集| 免费两性的视频网站| 无码一卡二卡三卡四卡 | 欧美男男大粗吊1069| 国产精品久久国产三级国 | 亚洲欧美日韩视频高清专区| 又爽又黄无遮挡高潮视频网站| 99久久人妻精品免费一区| 亚洲男人的天堂在线播放| 久久精品女人天堂av| 亚洲综合久久无码色噜噜赖水| 狂野欧美激情性xxxx按摩| 五月天激情国产综合婷婷婷| 精品国产乱码久久久久久免费| 乱中年女人伦av一区二区| 日韩人妻无码精品专区906188| 人妻无码中文专区久久五月婷 | 亚洲 欧美 变态 另类 综合 | 精品偷自拍另类在线观看| 新普新京亚洲欧美日韩国产 | 精品一二三区久久aaa片| 国产老妇伦国产熟女老妇视频 | 国产又粗又猛又大爽又黄| 国产农村妇女aaaaa视频 | 日本三级欧美三级人妇视频| 精品蜜臀久久久久99网站| 各处沟厕大尺度偷拍女厕嘘嘘| 日韩综合亚洲色在线影院| 中文字幕人妻丝袜成熟乱| 国产乱色国产精品播放视频| 国产精品无码专区av在线播放 | 国产又黄又潮娇喘视频在线观看| 亚洲全部无码中文字幕| 精品国产一区二区三区四区vr| 色伊人亚洲综合网站| 色欲天天婬色婬香视频综合网 | 亚洲第一av网站| 欧美性色大片在线观看|