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Recombinant Chicken Zona pellucida sperm-binding protein 3 (ZP3)

  • 中文名稱:
    雞ZP3重組蛋白
  • 貨號:
    CSB-CF027121CH
  • 說明書:
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    ZP3
  • Uniprot No.:
  • 別名:
    ZP3; ZPC; Zona pellucida sperm-binding protein 3; Sperm receptor; Zona pellucida C protein; Zona pellucida glycoprotein 3; Zp-3
  • 種屬:
    Gallus gallus (Chicken)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    21-360
  • 氨基酸序列
    YTPWDISWAARGDPSAWSWGAEAHSRAVAGSHPVAVQCQEAQLVVTVHRDLFGTGRLINAADLTLGPAACKHSSLNAAHNTVTFAAGLHECGSVVQVTPDTLIYRTLINYDPSPASNPVIIRTNPAVIPIECHYPRRENVSSNAIRPTWSPFNSALSAEERLVFSLRLMSDDWSTERPFTGFQLGDILNIQAEVSTENHVPLRLFVDSCVAALSPDGDSSPHYAIIDFNGCLVDGRVDDTSSAFITPRPREDVLRFRIDVFRFAGDNRNLIYITCHLKVTPADQGPDPQNKACSFNKARNTWVPVEGSRDVCNCCETGNCEPPALSRRLNPMERWQSRRFRRDAGKEVAADVVIGPVLLS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.
  • 基因功能參考文獻:
    1. chicken ZP3 was separated into four major and distinct isoforms with different pI in 2D-PAGE. PMID: 22776203
    2. Crystal structure of an avian homolog of ZP3 at 2.0 A resolution. The structure unveils the fold of a complete ZP domain module in a homodimeric arrangement required for secretion and reveals how EHP prevents premature incorporation of ZP3 into the ZP. PMID: 20970175
    3. ZP1, in addition to ZPC, plays a major role in the initial interactions between sperm and egg. PMID: 15115720
    4. Chick ZP3 is secreted to the apical aspect of chicken granulosa cells towards the perivitelline matrix. PMID: 9780332
    5. Involvement in the formation of quail zona pellucida PMID: 15503149

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  • 亞細胞定位:
    [Processed zona pellucida sperm-binding protein 3]: Secreted, extracellular space, extracellular matrix.; Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    ZP domain family, ZPC subfamily
  • 組織特異性:
    Detected in the ovarian perivitteline layer. Detected in granulosa cells in ovarian follicle (at protein level). Detected in granulosa cells in ovarian follicle.
  • 數據庫鏈接:


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