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  4. Recombinant Yersinia enterocolitica serotype O:8 / biotype 1B Cysteine protease yopT1 (yopT1)

Recombinant Yersinia enterocolitica serotype O:8 / biotype 1B Cysteine protease yopT1 (yopT1)

  • 中文名稱：
    小腸結腸炎耶爾森菌血清型O：8 /生物1B型yopT1重組蛋白
  • 貨號：
    CSB-YP375231YAK
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小腸結腸炎耶爾森菌血清型O：8 /生物1B型yopT1重組蛋白
  • 貨號：
    CSB-EP375231YAK
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小腸結腸炎耶爾森菌血清型O：8 /生物1B型yopT1重組蛋白
  • 貨號：
    CSB-EP375231YAK-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小腸結腸炎耶爾森菌血清型O：8 /生物1B型yopT1重組蛋白
  • 貨號：
    CSB-BP375231YAK
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小腸結腸炎耶爾森菌血清型O：8 /生物1B型yopT1重組蛋白
  • 貨號：
    CSB-MP375231YAK
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    yopT1
  • Uniprot No.：
  • 別名：
    yopT1; YEP0005; Cysteine protease yopT1; EC 3.4.22.-
  • 種屬：
    Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-322
  • 氨基酸序列
    MDSIHGHYHI QLSNYSAGEN LQSATPPEGV IGAHRVKVET ALSHSNRQKK LSATIKHNQS SRSMLDRKLT SDGKVNQRSS FTFSMIMYRM IHFVLSTRVP AVRESVANYG GNINFKFAQT KGAFLHQIIK HSDTARGACE ALCAHWIRSH AQGQSLFDQL YVGGRKGKFQ IDTLYSIKQL QIDGCKADVD QDEVTLDWLK KNGISERMIE RHCLLPTVDV TGTTGSEGPD QLLNAILDTN GIGYGYKKIS LSGQMSGHTI AAYVNENSGV TFFDPNFGEF HFSDKEKFSK WFTNSFWENS MYHYPLGVGQ SFSVFTFDSK EV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Cysteine protease, which is translocated into infected cells and plays a central role in pathogenesis by cleaving the C-terminus end of the human small GTPase RhoA/ARHA, a regulator of cytoskeleton. Once cleaved, ARHA loses its lipid modification, and is released from the cell membrane, leading to the subsequent disruption of actin cytoskeleton of the host cell.
  • 基因功能參考文獻：
    1. Data indicate that the composition of the polybasic region of the GTPases defines the specificity and efficiency of the YopT-induced cleavage. PMID: 18583524
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Peptidase C58 family
  • 數據庫鏈接：

    KEGG: yen:YEP0005



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