在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Xenopus laevis Nodal homolog (nodal)

  • 中文名稱:
    有爪蟾蜍nodal重組蛋白
  • 貨號(hào):
    CSB-YP820937XBE
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    有爪蟾蜍nodal重組蛋白
  • 貨號(hào):
    CSB-EP820937XBE
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    有爪蟾蜍nodal重組蛋白
  • 貨號(hào):
    CSB-EP820937XBE-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    有爪蟾蜍nodal重組蛋白
  • 貨號(hào):
    CSB-BP820937XBE
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    有爪蟾蜍nodal重組蛋白
  • 貨號(hào):
    CSB-MP820937XBE
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    nodal; nr1; Nodal homolog; Nodal-related protein 1; Xnr-1; Xnr1; nr-1
  • 種屬:
    Xenopus laevis (African clawed frog)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    282-406
  • 氨基酸序列
    NRNENHHLS IGSIPSRHVE NGKPLCRRVD MIVDFEDIGW SSWIVYPKKY NAYRCEGACP IPLNETFKPT NHAYMKSVVK LYQPERVECP LCVPVKMSPL SMLYYEGDEV VLRHHQEMIV EECGCS
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Essential for mesoderm formation and axial patterning during embryonic development. Activates the activin-like signaling pathway to induce dorsal and ventral mesoderm in animal cap ectoderm. In addition, also dorsalizes ventral marginal zone (VMZ) tissues during gastrulation. Acts in a downstream signaling cascade via cripto and cer1 to mediate cardiogenesis in embryonic mesoderm. Directs the orientation of the left-right axis by driving the left-specific gene cascade in the left lateral plate mesoderm.
  • 基因功能參考文獻(xiàn):
    1. FoxH1 and Grg4 occupy the Xnr1 enhancer, and Grg4 occupancy is dependent on the FoxH1 EH1 motif. Grg4 occupancy at the Xnr1 enhancer significantly decreases with Nodal activation or Smad2 overexpression, while FoxH1 occupancy is unaffected. These results suggest that Nodal-activated Smad2 physically displaces Grg4 from FoxH1, an essential feature of the transcriptional switch mechanism. PMID: 27085753
    2. Data suggest that Coco acts as a critical target of flow, suggesting that symmetry is broken by flow-mediated left-asymmetric release of Nodal repression at the midline. PMID: 20381352
    3. Unilateral expression of Xnr-1 in the left lateral plate mesoderm directs the orientation of the left-right axis by driving the left-specific gene cascade. PMID: 16281170
    4. asymmetric expression of Nodal-related 1 (Xnr1) begins in the posterior left lateral plate mesoderm shortly after the initiation of bilateral perinotochordal expression in the posterior tailbud PMID: 16959238
    5. Xnr1 and derriere are coexpressed in the posterior paraxial mesoderm at neurula stage, and with Coco define a posttranscriptionally regulated signaling center in the chain leading to an increased TGF-beta signal on the left side of the embryo. PMID: 17239842

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    TGF-beta family
  • 組織特異性:
    In the first phase of expression, localized to the vegetal region of the blastula. During gastrulation (stage 10.5), this expression disappears and instead becomes localized to the dorsal marginal zone, with enrichment in the organizer. During the second
  • 數(shù)據(jù)庫(kù)鏈接:

    KEGG: xla:378543

    UniGene: Xl.1037



主站蜘蛛池模板: 国产精品18禁污污网站| 国产在线午夜不卡精品影院| 久久国产免费观看精品a片| 新版天堂资源中文8在线| 日韩熟女精品一区二区三区 | 亚洲色欲久久久久综合网| 国产无套护士在线观看| 中文字幕在线不卡精品视频99 | 日韩精品中文字幕无码专区 | 精品人妻无码一区二区三区性| 美女av一区二区三区| 久久久久久99av无码免费网站| 色琪琪丁香婷婷综合久久| 播放灌醉水嫩大学生国内精品 | 国产精品久免费的黄网站| 国内精品久久久久精免费| 天天爽天天爽天天片a| 小荡货好紧好爽奶头大视频| 免费看成人欧美片爱潮app| 欧洲日本一线二线三线区本庄铃 | 97高清国语自产拍| 成人内射国产免费观看| 成 人 亚洲 综合天堂| 国产成人8x人网站在线视频| 黑人巨大精品欧美一区二区| 成av人片在线观看www| 国产av福利久久| 夜夜高潮天天爽欧美| 欧美在线看片a免费观看| 又湿又紧又大又爽又a视频| 人妻中文乱码在线网站| 黑森林福利视频导航| 新版资源天堂中文| 亚洲伊人色欲综合网无码中文 | 国产av熟女一区二区三区| 人妻无码中文字幕免费视频蜜桃| 黑人又粗又大又硬a片| 怡红院av一区二区三区| 99久久综合狠狠综合久久| 亚洲 欧美 清纯 校园 另类| 国产无遮挡又黄又爽高潮 |