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  4. Recombinant Xenopus laevis N-lysine methyltransferase SETD8-B (setd8-b)

Recombinant Xenopus laevis N-lysine methyltransferase SETD8-B (setd8-b)

  • 中文名稱：
    有爪蟾蜍kmt5a-b重組蛋白
  • 貨號：
    CSB-YP672091XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    有爪蟾蜍kmt5a-b重組蛋白
  • 貨號：
    CSB-EP672091XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    有爪蟾蜍kmt5a-b重組蛋白
  • 貨號：
    CSB-EP672091XBE-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    有爪蟾蜍kmt5a-b重組蛋白
  • 貨號：
    CSB-BP672091XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    有爪蟾蜍kmt5a-b重組蛋白
  • 貨號：
    CSB-MP672091XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    kmt5a-b
  • Uniprot No.：
  • 別名：
    kmt5a-b; mp36; setd8-bN-lysine methyltransferase KMT5A-B; EC 2.1.1.-; Histone-lysine N-methyltransferase KMT5A-B; EC 2.1.1.361; Lysine-specific methylase 5A-B; Mitotic phosphoprotein 36; SET domain-containing protein 8-B
  • 種屬：
    Xenopus laevis (African clawed frog)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-336
  • 氨基酸序列
    MGRGKKMSKP GDGRSGDVPE TCRTGGTNEN HPKMNGEVVH LGQPKIYSYM SPTKSPSGRP PLQEENSVAH HESKNLGKPT TETRKKAEVE KKRISSATEL SVKSSKQRET ECNSIGEYFQ TKQELTDVQR NTALTPVDKL QSQKMVKNKS QRRKAQRKKS PNRKLTDYYP VRRSCRKSKT ELESEEKMRI DELIQTGKED GMKMDMIIGK GRGVIATRDF QRGEFVVEYH GDLIEITDAK RREASYAQDS ATGCYMYYFQ YLNKTYCIDA TRETGRLGRL INHSKSGNCH TKLHNISNVP HLILVASRDI LVGEELLYDY GDRRKSSIEA HPWLKN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis.
  • 亞細胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, PR/SET subfamily
  • 數(shù)據(jù)庫鏈接：

    KEGG: xla:398318

    UniGene: Xl.2518



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