在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

IFIT5 Antibody

  • 中文名稱:
    IFIT5兔多克隆抗體
  • 貨號:
    CSB-PA984140
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from Jurkat cells, using IFIT5 antibody.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) IFIT5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    IFIT5
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human IFIT5.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Interferon-induced RNA-binding protein involved in the human innate immune response. Has a broad and adaptable RNA structure recognition important for RNA recognition specificity in antiviral defense. Binds precursor and processed tRNAs as well as poly-U-tailed tRNA fragments. Specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and selectively binds AT-rich dsDNA. Additionally, as a mediator in innate immunity, regulates positively IKK-NFKB signaling by sinergizing the recruitment of IKK to MAP3K7.
  • 基因功能參考文獻(xiàn):
    1. IFIT5 promotes SeV-induced IKK phosphorylation and NF-kappaB activation by regulating the recruitment of IKK to TAK1. PMID: 26334375
    2. show that IFIT5 binds precursor and processed tRNAs, as well as other RNA polymerase III transcripts. Our findings establish the RNA recognition specificity of the human innate immune response protein IFIT5 PMID: 25092312
    3. TRIF-N-terminal helical domain shares structural similarity with IFIT5. PMID: 24311583
    4. IFIT5 consists of 24 alpha-helices that pack into a special "V"-like structure. PMID: 23774268
    5. IFIT5 recognizes cellular RNA instead of protein partners. PMID: 23317505
    6. crystal structures of human IFIT5, its complex with PPP-RNAs, and an amino-terminal fragment of IFIT1 PMID: 23334420

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell projection, ruffle membrane. Note=Colocalized with DDX58/RIG-I at cell surface ruffles. Localizes to actin-rich protrusions from the apical cell surface.
  • 蛋白家族:
    IFIT family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 13328

    OMIM: 616135

    KEGG: hsa:24138

    STRING: 9606.ENSP00000360860

    UniGene: Hs.252839



主站蜘蛛池模板: 亚洲成在人线在线播放无码| 亚洲第一女人av| a在线亚洲男人的天堂| 99精品国产一区二区三区不卡 | 午夜精品久久久久久久爽| 免费无码一区二区三区a片| 天无日天天射天天视| 亚洲国产欧美日韩精品一区二区三区| 成人无码一区二区三区网站| 中国老熟女重囗味hdxx| 久久成人麻豆午夜电影| 精品亚洲国产成av人片传媒| 亚洲欧洲自偷自拍图片| 欧美天天拍在线视频| 亚洲精品乱码久久久久久自慰| 国产精品一线二线三线| 欧美精品18videosex性欧美| 国产福利萌白酱精品tv一区| 亚洲日本中文字幕乱码在线| 亚洲国产丝袜精品一区| 天天摸夜夜添夜夜无码| 欧美人与动人物牲交免费观看久久| 免费又黄又裸乳的视频| 一本大道久久香蕉成人网| 国产精品av一区二区三区不卡蜜 | 三级全黄的视频在线观看| 色欲香天天天综合网站| 日本高清无卡码一区二区久久| 午夜亚洲www湿好大| 少妇爽到呻吟的视频| 狠狠色噜噜狠狠狠888米奇| 免费久久人人爽人人爽av| 久久精品国产99国产精偷| 国色精品卡一卡2卡3卡4卡在线| 午夜免费啪视频观看视频 | 欧美肉大捧一进一出免费视频| 艳妇臀荡乳欲伦交换在线播放| 亚洲国产天堂久久久久久| 成人乱码一区二区三区四区| 国产精品三级一区二区| 高清无码视频直接看|