Recombinant Varicella-zoster virus Serine/threonine-protein kinase UL13 homolog (ORF47), partial

中文名稱：

Recombinant Varicella-zoster virus Serine/threonine-protein kinase UL13 homolog(ORF47) ,partial
貨號：

CSB-YP747721VAQ
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Varicella-zoster virus Serine/threonine-protein kinase UL13 homolog(ORF47) ,partial
貨號：

CSB-EP747721VAQ
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Varicella-zoster virus Serine/threonine-protein kinase UL13 homolog(ORF47) ,partial
貨號：

CSB-EP747721VAQ-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Varicella-zoster virus Serine/threonine-protein kinase UL13 homolog(ORF47) ,partial
貨號：

CSB-BP747721VAQ
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Varicella-zoster virus Serine/threonine-protein kinase UL13 homolog(ORF47) ,partial
貨號：

CSB-MP747721VAQ
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ORF47
Uniprot No.：

Q6YP73
別名：

ORF47Serine/threonine-protein kinase UL13 homolog; Protein kinase ORF47; EC 2.7.11.1
種屬：

Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Multifunctional serine/threonine kinase that plays a role in several processes including egress of virus particles from the nucleus, modulation of the actin cytoskeleton and regulation of viral and cellular gene expression. Regulates the nuclear localization of viral envelopment factor proteins 24 and 27, by phosphorylating the protein kinase ORF66, indicating a role in nuclear egress. Disrupts host nuclear lamins, including LMNA and LMNB1. Phosphorylates the viral Fc receptor composed of glycoproteins E (gE) and I (gI). Phosphorylation of glycoprotein E (gE) by UL13 alters its subcellular localization, from the host early endosome to the plasma membrane. Participates in the transcriptional regulation of cellular and viral mRNAs mainly by phosphorylating the viral transcriptional regulator IE63.
基因功能參考文獻：
1. ORF47p is involved in the atypical phosphorylation of IRF3 during VZV infection PMID: 21347389
2. VZV ORF47 is important for replication in immature dendritic cells and for spread to other cells PMID: 15913699
亞細胞定位：

Virion tegument. Host nucleus.
蛋白家族：

Protein kinase superfamily, Ser/Thr protein kinase family
數據庫鏈接：

KEGG: vg:1487678