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  4. Recombinant Thermotoga maritima Imidazole glycerol phosphate synthase subunit HisH (hisH)

Recombinant Thermotoga maritima Imidazole glycerol phosphate synthase subunit HisH (hisH)

  • 中文名稱：
    海棲熱袍菌hisH重組蛋白
  • 貨號：
    CSB-YP894420TNJ
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    海棲熱袍菌hisH重組蛋白
  • 貨號：
    CSB-EP894420TNJ
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    海棲熱袍菌hisH重組蛋白
  • 貨號：
    CSB-EP894420TNJ-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    海棲熱袍菌hisH重組蛋白
  • 貨號：
    CSB-BP894420TNJ
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    海棲熱袍菌hisH重組蛋白
  • 貨號：
    CSB-MP894420TNJ
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    hisH
  • Uniprot No.：
  • 別名：
    hisH; TM_1038Imidazole glycerol phosphate synthase subunit HisH; EC 4.3.2.10; IGP synthase glutaminase subunit; EC 3.5.1.2; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; TmHisH
  • 種屬：
    Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-201
  • 氨基酸序列
    MRIGIISVGP GNIMNLYRGV KRASENFEDV SIELVESPRN DLYDLLFIPG VGHFGEGMRR LRENDLIDFV RKHVEDERYV VGVCLGMQLL FEESEEAPGV KGLSLIEGNV VKLRSRRLPH MGWNEVIFKD TFPNGYYYFV HTYRAVCEEE HVLGTTEYDG EIFPSAVRKG RILGFQFHPE KSSKIGRKLL EKVIECSLSR R
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  • 基因功能參考文獻：
    1. Data show that imidazole glycerol phosphate synthase (IGPS) enzymatic activity can be impaired by small molecules that bind along the allosteric pathway connecting the orthosteric and allosteric sites, without competing with endogenous ligands. PMID: 27797506
    2. Data show that in the apo-complex, f3 is a central community connected to all other communities in the imidazole glycerol phosphate synthase (IGPS) heterodimer and includes the most stable contacts between the HisF and HisH domains. PMID: 22586084
  • 亞細胞定位：
    Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    KEGG: tma:TM1038

    STRING: 243274.TM1038



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