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  4. Recombinant Target of rapamycin homolog (let-363), partial

Recombinant Target of rapamycin homolog (let-363), partial

  • 中文名稱：
    秀麗隱桿線蟲let-363重組蛋白
  • 貨號：
    CSB-YP836117CXY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲let-363重組蛋白
  • 貨號：
    CSB-EP836117CXY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲let-363重組蛋白
  • 貨號：
    CSB-EP836117CXY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲let-363重組蛋白
  • 貨號：
    CSB-BP836117CXY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲let-363重組蛋白
  • 貨號：
    CSB-MP836117CXY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    let-363
  • Uniprot No.：
  • 別名：
    let-363; CeTor; B0261.2; Target of rapamycin homolog; EC 2.7.11.1; CeTOR; Lethal protein 363
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Serine/threonine-protein kinase that regulates the mRNA translation machinery, probably by modulating the activity of translation factors such as eIF-4G and eIF-2. It may have some protein kinase activity instead of lipid kinase activity. May play a role in P-granule degradation by autophagy in somatic cells during embryogenesis. Required, during larval development, for the establishment of the proper number of germline progenitors, probably upstream of rsks-1 and ife-1. Required for larval development. May act as a mediator of lifespan regulation by insulin signaling and nutrient sensing.
  • 基因功能參考文獻：
    1. Dafachronic acid signaling through let-363 is essential for diet restriction-mediated longevity. PMID: 25209682
    2. influence on lifespan PMID: 14668850
    3. C. elegans target of rapamycin (TOR) and the DAF-2/insulin-signaling pathways cross-talk with pep-2 PMID: 15155758
    4. Mutations result in dauer-like larval arrest, implying that CeTOR (let-363)regulates dauer diapause. PMID: 15253933
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    PI3/PI4-kinase family
  • 組織特異性：
    Ubiquitous. Expressed in all major tissues and organs, including the intestine, gonads and hypodermal cells. Expressed in neurons.
  • 數據庫鏈接：

    KEGG: cel:CELE_B0261.2

    STRING: 6239.B0261.2a.2

    UniGene: Cel.19302



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