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Recombinant Streptococcus mutans serotype c Glucosyltransferase-I (gtfB), partial

  • 貨號:
    CSB-EP357547FMR
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    gtfB
  • Uniprot No.:
  • 別名:
    (GTF-I)(Dextransucrase)(Sucrose 6-glucosyltransferase)
  • 種屬:
    Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    26.8 kDa
  • 表達區域:
    426-597aa
  • 氨基酸序列
    WLHFLMNFGNIYANDPDANFDSIRVDAVDNVDADLLQIAGDYLKAAKGIHKNDKAANDHLSILEAWSDNDTPYLHDDGDNMINMDNKLRLSLLFSLAKPLNQRSGMNPLITNSLVNRTDDNAETAAVPSYSFIRAHDSEVQDLIRDIIKAEINPNVVGYSFTMEEIKKAFEI
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris.
  • 基因功能參考文獻:
    1. mannans located on the outer surface of Candida albicans cell-wall mediates Streptococcus mutans GtfB binding, enhancing glucan-matrix production and modulating bacterial-fungal association. PMID: 28617874
    2. critical role for RegM in regulation of expression of both gtfBC and ftf. PMID: 15500982
    3. RNA dot blot analysis demonstrated that transcriptions of the gtfB gene, which encode GTF-I were downregulated. These findings suggest that orf1 and orf2 are associated with positive regulation of the gtfB gene. PMID: 19416450
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Glycosyl hydrolase 70 family
  • 數據庫鏈接:


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