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Your Good Partner in Biology Research

DECR1 Antibody

  • 中文名稱:
    DECR1兔多克隆抗體
  • 貨號:
    CSB-PA087606
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA087606(DECR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA087606(DECR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Human endometrial carcinoma tissue, Human colon cancer tissue, human fetal liver tissue, PC3 cells, Primary antibody: CSB-PA087606(DECR1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    DECR1
  • 別名:
    1200012F07Rik antibody; 2 antibody; 2,4 dienoyl CoA reductase [NADPH] antibody; 2,4 dienoyl CoA reductase 1 antibody; 2,4 dienoyl CoA reductase mitochondrial antibody; 2,4-dienoyl-CoA reductase; mitochondrial antibody; 4 enoyl CoA reductase antibody; 4-dienoyl-CoA reductase [NADPH] antibody; 4-enoyl-CoA reductase [NADPH] antibody; DECR 1 antibody; DECR antibody; DECR_HUMAN antibody; DECR1 antibody; Nadph antibody; OTTMUSP00000004962 antibody; RP23-338J24.3 antibody; SDR18C1 antibody; Short chain dehydrogenase/reductase family 18C member 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide of Human DECR1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
  • 基因功能參考文獻:
    1. Our study is the first to demonstrate the novel function of UA in NET formation and may provide insight into the management of patients with hyperuricemia. PMID: 24326071
    2. Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase PMID: 15531764
    3. Sequence alignment indicates that there are five highly conserved acidic residues, one of which (E276) might act as a proton donor. PMID: 15629123
    4. mutational defects cause chronic granulomatous disease in humans PMID: 18193341
    5. The luminal NADPH pool is an important antiapoptotic factor in neutrophil granulocytes. PMID: 18472006
    6. The TT genotype of C677T polymorphism in the MTHFR gene contributes to genetic susceptibility of acute ischemic stroke in a Singapore population. PMID: 19049547

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  • 相關疾病:
    2,4-dienoyl-CoA reductase deficiency (DECRD)
  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    Short-chain dehydrogenases/reductases (SDR) family, 2,4-dienoyl-CoA reductase subfamily
  • 組織特異性:
    Heart = liver = pancreas > kidney >> skeletal muscle = lung.
  • 數據庫鏈接:

    HGNC: 2753

    OMIM: 222745

    KEGG: hsa:1666

    STRING: 9606.ENSP00000220764

    UniGene: Hs.492212



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