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  4. Recombinant Staphylococcus aureus Clumping factor B (clfB), partial

Recombinant Staphylococcus aureus Clumping factor B (clfB), partial

  • 中文名稱：
    Recombinant Staphylococcus aureus Clumping factor B(clfB) ,partial
  • 貨號：
    CSB-YP646047FLF
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Staphylococcus aureus Clumping factor B(clfB) ,partial
  • 貨號：
    CSB-EP646047FLF
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Staphylococcus aureus Clumping factor B(clfB) ,partial
  • 貨號：
    CSB-EP646047FLF-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Staphylococcus aureus Clumping factor B(clfB) ,partial
  • 貨號：
    CSB-BP646047FLF
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Staphylococcus aureus Clumping factor B(clfB) ,partial
  • 貨號：
    CSB-MP646047FLF
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    clfB
  • Uniprot No.：
  • 別名：
    clfB; SAOUHSC_02963Clumping factor B; Fibrinogen receptor B; Fibrinogen-binding protein B
  • 種屬：
    Staphylococcus aureus (strain NCTC 8325)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps. Partly responsible for mediating bacterial attachment to the highly keratinized squamous epithelial cells from the nasal cavity via an interaction with cytokeratin K10 (K10). Also promotes bacterial attachment to cultured keratinocytes, possibly through an interaction with cytokeratin K10. Binds mouse cytokeratin K10. Activates human platelet aggregation.
  • 基因功能參考文獻：
    1. Interaction between Staphylococcus aureus Clumping Factor B and squamous epithelial cell envelope protein Loricrin is strengthened by tensile force. This force-sensitive mechanism provides the cells with a means to modulate their adhesive properties during the colonization of host surfaces. PMID: 29208742
    2. ClfB is a key adhesion molecule for the interaction of S. aureus with atopic dermatitis corneocytes PMID: 28373353
    3. Rot and the Agr system in S. aureus NCTC8325 can affect the bacterial binding ability to human fibrinogen (Fg) under different bacterial growth phases through regulating clfB transcription. PMID: 21701848
    4. ClfB protein is a major determinant of nasal-persistent S. aureus carriage. PMID: 18198942
  • 亞細胞定位：
    Secreted, cell wall; Peptidoglycan-anchor.
  • 蛋白家族：
    Serine-aspartate repeat-containing protein (SDr) family
  • 數據庫鏈接：


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