在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Spermophilus beecheyi Cellular tumor antigen p53 (TP53)

  • 中文名稱:
    Recombinant Spermophilus beecheyi Cellular tumor antigen p53(TP53)
  • 貨號:
    CSB-YP720691FJZ
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Spermophilus beecheyi Cellular tumor antigen p53(TP53)
  • 貨號:
    CSB-EP720691FJZ
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Spermophilus beecheyi Cellular tumor antigen p53(TP53)
  • 貨號:
    CSB-EP720691FJZ-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Spermophilus beecheyi Cellular tumor antigen p53(TP53)
  • 貨號:
    CSB-BP720691FJZ
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Spermophilus beecheyi Cellular tumor antigen p53(TP53)
  • 貨號:
    CSB-MP720691FJZ
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    TP53; Cellular tumor antigen p53; Tumor suppressor p53; Fragment
  • 種屬:
    Spermophilus beecheyi (Beechey ground squirrel) (Otospermophilus beecheyi)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-314
  • 氨基酸序列
    DLWNLLPENN VLSPVLSPPM DDLLLSSEDV ENWFDKGPDE ALQMSAAPAP KAPTPAASTL AAPTPAISWP LSSSVPSQNT YPGVYGFRLG FIHSGTAKSV TCTYSPSLNK LFCQLAKTCP VQLWVDSTPP PGTRVRAMAI YKKSQHMTEV VRRCPHHERC SDSDGLAPPQ HLIRVEGNLR AEYLDDRNTF RHSVVVPYEP PEVGSESTTI HYNYMCNSSC MGGMNRRPIL TIITLEDSSG NLLGRNSFEV RVCACPGRDR RTEEENFRKR GEPCPEPPPG STKRALPTGT NSSPQPKKKP LDGEYFTLKI RGRA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2. However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation. Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2.
  • 相關疾病:
    p53 is found in increased amounts in a wide variety of transformed cells. p53 is frequently mutated or inactivated in many types of cancer.
  • 亞細胞定位:
    Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 蛋白家族:
    P53 family


主站蜘蛛池模板: 亚洲精品无码国产片| 国产成人精品一区二区秒播| 人人妻人人澡av天堂香蕉| 亚洲精品成人网站在线观看| 久久久久成人精品免费播放动漫| 疯狂做受xxxx高潮不断| 又黄又粗又爽免费观看| 亚洲精品一卡2卡三卡4卡| 国产猛烈高潮尖叫视频免费| 女人18毛片水最多| 亚洲国产成人精品无码区在线软件 | 国产成人欧美综合在线影院| 99热这里只就有精品22| 久久婷婷五月综合中文字幕| 成人免费毛片内射美女-百度| 久久精品中文字幕| 中文字幕日韩精品亚洲一区| 亚洲精品午夜一区人人爽| 国产热re99久久6国产精品首页 | 午夜美女裸体福利视频| 国内精品一区二区三区不卡| 亚洲女同一区二区| 精品亚洲一区二区三区四区五区 | 国产乱人伦精品一区二区| 国产伦子系列沙发午睡| 久久这里有精品国产电影网| 大尺度无遮挡激烈床震网站| 亚洲国内成人精品网| 精品免费看国产一区二区 | 无遮无挡爽爽免费毛片| 日韩精品一区二区三区影院| 野外被强j到高潮免费观看| av人摸人人人澡人人超碰下载| 亚洲妇女自偷自偷图片| 精品久久久无码中文字幕| 国产无遮挡又黄又爽免费网站| 99久热re在线精品视频| 尤物精品国产第一福利网站| 国产精品亚洲欧美大片在线看| 国产成人综合久久精品推最新| 少妇人妻精品无码专区视频|