在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein (env), partial

Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein (env), partial

  • 中文名稱：
    Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein(env),partial
  • 貨號：
    CSB-YP333624SFU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein(env),partial
  • 貨號：
    CSB-EP333624SFU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein(env),partial
  • 貨號：
    CSB-EP333624SFU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein(env),partial
  • 貨號：
    CSB-BP333624SFU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein(env),partial
  • 貨號：
    CSB-MP333624SFU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    env
  • Uniprot No.：
  • 別名：
    envEnvelope glycoprotein; Env polyprotein) [Cleaved into: Surface protein; SU; Glycoprotein 52; gp52); Transmembrane protein; TM; Glycoprotein 36; gp36)]
  • 種屬：
    Sheep pulmonary adenomatosis virus (Jaagsiekte sheep retrovirus) (JSRV)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    The envelope proteins induce cell transformation leading to ovine pulmonary adenocarcinoma (OPA), a contagious lung cancer of sheep and goat. They bind to the HYAL2 receptor for cell entry. Env proteins probably do not act as oncogenes by themselves, but may rather liberate an oncogenic factor that would normally be negatively regulated. One mechanism of transformation seems to involve activation of the phosphoinositide-3-OH kinase (PI3K)/Akt pathway but does not involve the virus receptor HYAL2, and the other seems to involve Env binding to HYAL2, HYAL2 degradation, and activation of the MST1R receptor tyrosine kinase, which is normally suppressed by HYAL2.
  • 基因功能參考文獻：
    1. BST2B acts differently from BST2A by leading to a reduction in Jaagsiekte sheep retrovirus Env incorporation into viral particles, which ultimately results in the release of virions that are less infectious. PMID: 25339764
    2. study reveals critical determinants in SU subunits of JSRV and ENTV Env proteins that likely regulate their local structure and thereby differential receptor-mediated fusion activation at low pH; findings explain, in part, their distinct viral infectivity PMID: 22018783
    3. The authors observed that Env of Jaagsiekte sheep retrovirus induced the expression of a tumor suppressor, Sprouty2, suggesting a correlation between Env-effect and Sprouty2 expression. PMID: 20678191
    4. These data strongly suggest that the JSRV Env functions as a dominant oncoprotein in the natural immunocompetent host and that JSRV can induce ovine pulmonary adenocarcinoma in the absence of viral spread. PMID: 16873259
    5. The role of the env transmembrane cytoplasmic tail in JSRV transformation was studied. PMID: 16873263
    6. JSRV Env protein is capable of inducing tumors in transgenic mice, and in other cell types besides lung epithelial cells. PMID: 17043760
    7. signal peptide of the JSRV Env (JSE-SP) is 80 amino acid residues in length and contains putative nuclear localization and export signals, in addition to an arginine-rich RNA binding motif PMID: 19244321
    8. In this study, the authors found that the betaretrovirus Jaagsiekte sheep retrovirus (JSRV) encodes within the env gene a trans-acting factor (Rej) necessary for the synthesis of Gag protein from unspliced viral RNA. PMID: 19776124
    9. Rej response element-containing RNA relocalized Rej protein from the nucleus to the cytoplasm in 293 and rat 208F cells, suggesting binding of Rej to the Rej response element. PMID: 19776134

    顯示更多

    收起更多

  • 亞細胞定位：
    [Surface protein]: Virion membrane; Peripheral membrane protein.; [Transmembrane protein]: Virion membrane; Single-pass type I membrane protein.
  • 數據庫鏈接：

    KEGG: vg:1490021



主站蜘蛛池模板： 欧美 日韩 人妻 高清 中文| 丰满少妇被猛烈进入试看| 日韩激情无码不卡码| 波多野结衣一区二区三区高清| 久久精品成人免费观看三| 最新精品国偷自产在线老年人| 国产精品视频一区二区三区不卡| 色综合欧美在线视频区| 四虎国产精亚洲一区久久特色| 国产av成人无码精品网站| 亚洲欧美综合精品成人导航 | 国产97超碰人人做人人爱| 又黄又湿啪啪响18禁| 国产成人无码一区二区在线播放| 奇米影视777四色米奇影院| 亚洲偷自拍国综合色帝国| 制服丝袜亚洲中文欧美在线| 国产综合内射日韩久| 99蜜桃臀久久久欧美精品网站| 神马午夜福利不卡片在线| 香蕉97超级碰碰碰免费公开| 亚洲中文字幕无码av在线| 欧洲亚洲色一区二区色99| 色一情一伦一区二区三| 人妻三级日本三级日本三级极 | 人人妻人人澡人人爽人人精品浪潮| 女人被躁到高潮免费视频| 永久黄网站色视频免费看| 欧美老妇与zozoz0交| 亚洲日韩av无码一区二区三区人| 久久青青草原国产最新片完整| 中文字幕亚洲码在线| 久久久www成人免费无遮挡大片 | 亚洲一卡2卡3卡4卡精品 | 色视频无码专区在线观看| 久久精品无码av| 男女裸交免费无遮挡全过程| 欧美精品九九久久久久久久久| 国产成人啪精品午夜网站a片免费| 性xxxx搡xxxxx搡欧美| 精品国产一区二区三区麻豆|