Recombinant Sex-determination protein fem-3 (fem-3)

中文名稱：

秀麗隱桿線蟲fem-3重組蛋白
貨號：

CSB-YP339486CXY
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲fem-3重組蛋白
貨號：

CSB-EP339486CXY
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲fem-3重組蛋白
貨號：

CSB-EP339486CXY-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲fem-3重組蛋白
貨號：

CSB-BP339486CXY
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲fem-3重組蛋白
貨號：

CSB-MP339486CXY
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

fem-3
Uniprot No.：

P34691
別名：

fem-3; C01F6.4Sex-determination protein fem-3; Ce-FEM-3; Feminization of XX and XO animals protein 3
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區域：

1-388
氨基酸序列

MEVDPGSDDV EADRETRAQK LKLKRNVKFR AQMRRFDEYC GVTNLTVDDL NWPLISGIPL QRQRLTGATY YDDSLLDQNP WDEFSIDRFL EITSIQLITA GAGYERNDEI TRFVFQRTMK TIVTYCNFMY DLARRNGKVQ ITRFELQDLI HRDEFRFYMY FRQFLPNPDP NCTAFSNHYT SLLHTLYFNI PGMPQFWNNS QMYNYAATRG QRLVQNIAAF YPPEYFWNED ESKYHTTFVV PRGTEFSKFY ARRFHEALGM PPLENEIITV LDWLAKLCIL EIVYHTTIWC DITGFGGLPR IEHYRLAMEN VEDIIFDLAI DDFSISRLQL QISPFEISRY SPLDVSGYYE TIKRKKDIEE YQNRFYEVHY SDDVRIMNVY ATDCSRKR
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Required for male development. In XO (male) animals, fem-3 directs male differentiation in all tissues. In XX (hermaphrodite) animals, it specifies the first 80 or so germ cells to be sperm. Negatively regulates male development when bound to tra-2. Together with fem-2 associates with the CBC(fem-1) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of tra-1.
基因功能參考文獻：
1. It was shown that FEM-3 is exclusively present in germ cells that are committed to spermatogenesis. In fem- 3(gf)/+ heterozygotes, mutant fem-3 gain-of-function transcripts are more abundant than their wild-type counterpart. PMID: 22635404
2. Pumilio-fem-3 mRNA binding factor (PUF) RNA-binding proteins achieve that specificity through variations on a conserved scaffold. PMID: 22205700
數據庫鏈接：

KEGG: cel:CELE_C01F6.4

STRING: 6239.C01F6.4a

UniGene: Cel.18200