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  4. Recombinant Serine/threonine-protein phosphatase PP1-beta (gsp-2)

Recombinant Serine/threonine-protein phosphatase PP1-beta (gsp-2)

  • 中文名稱：
    秀麗隱桿線蟲gsp-2重組蛋白
  • 貨號：
    CSB-YP343753CXY
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲gsp-2重組蛋白
  • 貨號：
    CSB-EP343753CXY
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲gsp-2重組蛋白
  • 貨號：
    CSB-EP343753CXY-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲gsp-2重組蛋白
  • 貨號：
    CSB-BP343753CXY
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲gsp-2重組蛋白
  • 貨號：
    CSB-MP343753CXY
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    gsp-2
  • Uniprot No.：
  • 別名：
    gsp-2; Ce-glc-7beta; CeGLC-7beta; glc-7; F56C9.1; Serine/threonine-protein phosphatase PP1-beta; EC 3.1.3.16; CeGLC-7-beta; Glc seven-like phosphatase 2
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-333
  • 氨基酸序列
    MDVEKLNLDN IISRLLEVRG SKPGKNVQLT ESEIKGLCQK SREIFLSQPI LLELEAPLKI CGDVHGQYYD LLRLFEYGGF PPESNYLFLG DYVDRGKQSL ETICLLLAYK IKYPENFFLL RGNHECASIN RIYGFYDECK RRYNIKLWKT FTDCFNCLPV AAIIDEKIFC CHGGLSPDLQ SMEQIRRIMR PTDVPDQGLL CDLLWSDPDK DVTGWGENDR GVSFTFGPEV VAKFLHKHDL DLICRAHQVV EDGYEFFAKR QLVTLFSAPN YCGEFDNAGS MMTVDETLMC SFQILKPADK KKYPYGAGGV GSNRPVTPPR NAPAAQPKKG AKK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Serine/threonine-protein phosphatase essential for chromosomal dynamics during meiosis and mitosis. During meiosis, promotes chromosomal cohesion and germline immortality via a small RNA-mediated genome silencing pathway. Antagonizes the function of air-2 kinase during meiosis I and mitosis to promote chromatid cohesion and spindle attachment. Dephosphorylates histone H3 at 'Ser-10' (Probable). Dephosphorylates histone H3 at 'Thr-3' (Probable). Also involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation. Promotes small RNA-mediated genome silencing over multiple generations. Essential for embryogenesis.
  • 基因功能參考文獻：
    1. LAB-1 is required to target GSP-2 to early meiotic nuclei. PMID: 22927794
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    PPP phosphatase family, PP-1 subfamily
  • 組織特異性：
    Expressed in gonads, nervous system, intestine and muscles.
  • 數據庫鏈接：

    KEGG: cel:CELE_F56C9.1

    STRING: 6239.F56C9.1.1

    UniGene: Cel.24408



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