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  4. Recombinant Schizosaccharomyces pombe Uncharacterized protein C16E9.01c (SPBC16E9.01c, SPBP16F5.09c)

Recombinant Schizosaccharomyces pombe Uncharacterized protein C16E9.01c (SPBC16E9.01c, SPBP16F5.09c)

  • 中文名稱：
    龐貝裂殖酵母php4重組蛋白
  • 貨號：
    CSB-YP515671SXV
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母php4重組蛋白
  • 貨號：
    CSB-EP515671SXV
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母php4重組蛋白
  • 貨號：
    CSB-EP515671SXV-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    龐貝裂殖酵母php4重組蛋白
  • 貨號：
    CSB-BP515671SXV
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母php4重組蛋白
  • 貨號：
    CSB-MP515671SXV
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    php4
  • Uniprot No.：
  • 別名：
    php4; SPBC16E9.01c; SPBP16F5.09c; CCAAT-binding factor complex subunit php4
  • 種屬：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-295
  • 氨基酸序列
    MESSKSPSEV EKSSSASPAP QKPMIRVSKQ WVVPPRPKPG RKPALDALGR RKAPIKPRPG PTSALSVEEA KFRVREKQYQ DTIGKLQKEN NELLEQLEML QAQLKNSTLD SPKEVEVNSE VVKPDSATTE NENRYVNQYN YPVEPPCAKN AVYTEIPIEL DPHAFLGDSA KRIRVDSDSK DAKSVPSENG RIRVSMSPQN EINFTPENPA VMEKIRKRGV CNSVEGCLYS GSPKSVKRVR ESEETKVYAQ LLIDLHKSSK SAPMLKAGPS IAFKLPTMEP NFNDVRPVTS ISSSS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the transcription regulatory CCAAT-binding complex. Required for the reprogramming of the cell for iron use. Downregulates pcl1, sdh4, and isa1 underlow-iron conditions.
  • 基因功能參考文獻：
    1. Study aimed to biochemically define these protein-protein and protein-metal interactions. Grx4 was found to bind a [2Fe-2S] cluster with spectroscopic features similar to other CGFS glutaredoxins. Grx4 and Php4 also copurify as a complex with a [2Fe-2S] cluster that is spectroscopically distinct from the cluster on Grx4these results show that Grx4 controls Php4 function through binding of a bridging [2Fe-2S] cluster. PMID: 28725905
    2. Grx4 independently governs the Php4 and Fep1 repressors through metal transfer. total or partial disassembly of the Grx4-Fra2 cluster actively participates in iron-containing Fep1 activation PMID: 25806539
    3. Grx4 and Crm1 are novel components involved in the mechanism by which Php4 is inactivated by iron in a Fep1-independent manner. PMID: 19502236
  • 亞細胞定位：
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole.
  • 數據庫鏈接：


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