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Recombinant Schizosaccharomyces pombe Ubiquitin conjugation factor E4 (ufd2), partial

  • 中文名稱:
    龐貝裂殖酵母ufd2重組蛋白
  • 貨號:
    CSB-YP862086SXV
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    龐貝裂殖酵母ufd2重組蛋白
  • 貨號:
    CSB-EP862086SXV
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    龐貝裂殖酵母ufd2重組蛋白
  • 貨號:
    CSB-EP862086SXV-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    龐貝裂殖酵母ufd2重組蛋白
  • 貨號:
    CSB-BP862086SXV
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    龐貝裂殖酵母ufd2重組蛋白
  • 貨號:
    CSB-MP862086SXV
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ufd2
  • Uniprot No.:
  • 別名:
    ufd2; SPAC145.04; SPAC20H4.10Ubiquitin conjugation factor E4; EC 2.3.2.-; Ubiquitin fusion degradation protein 2; UB fusion protein 2
  • 種屬:
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    E4 ubiquitin chain-elongation enzyme specifically involved in polyubiquitin chain assembly. Binds to cdc48 and elongates mono- and diubiquitinated ERAD substrates presented by the ufd1-npl4-cdc48 (UNC) AAA ATPase complex to a chain length of 4 to 6 ubiquitin moieties. Delivers these polyubiquitinated substrates to downstream ERAD components, which target them to the proteasome. Enhances ubiquitination at 'Lys-48', but not at 'Lys-29' of the Ub moiety.
  • 基因功能參考文獻:
    1. Ufd2 induces cell death in prolonged nutrient deprivation, that Sds23/Psp1/Moc1 may be a target protein of the ubiquitin-fusion degradation pathway for regulation of cell viability under this stress condition. PMID: 23640764
    2. Data show that ufd2 mutants exhibiting resistance to cisplatin. PMID: 21247416
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Ubiquitin conjugation factor E4 family
  • 數據庫鏈接:


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