在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Schizosaccharomyces pombe Chromatin-associated protein swi6 (swi6)

Recombinant Schizosaccharomyces pombe Chromatin-associated protein swi6 (swi6)

  • 中文名稱：
    龐貝裂殖酵母swi6重組蛋白
  • 貨號：
    CSB-YP340241SXV
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母swi6重組蛋白
  • 貨號：
    CSB-EP340241SXV
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母swi6重組蛋白
  • 貨號：
    CSB-EP340241SXV-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    龐貝裂殖酵母swi6重組蛋白
  • 貨號：
    CSB-BP340241SXV
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母swi6重組蛋白
  • 貨號：
    CSB-MP340241SXV
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    swi6
  • Uniprot No.：
  • 別名：
    swi6; SPAC664.01c; SPAC824.10c; Chromatin-associated protein swi6
  • 種屬：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-328
  • 氨基酸序列
    MKKGGVRSYR RSSTSKRSVI DDDSEPELPS MTKEAIASHK ADSGSSDNEV ESDHESKSSS KKLKENAKEE EGGEEEEEDE YVVEKVLKHR MARKGGGYEY LLKWEGYDDP SDNTWSSEAD CSGCKQLIEA YWNEHGGRPE PSKRKRTARP KKPEAKEPSP KSRKTDEDKH DKDSNEKIED VNEKTIKFAD KSQEEFNENG PPSGQPNGHI ESDNESKSPS QKESNESEDI QIAETPSNVT PKKKPSPEVP KLPDNRELTV KQVENYDSWE DLVSSIDTIE RKDDGTLEIY LTWKNGAISH HPSTITNKKC PQKMLQFYES HLTFRENE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Involved in the repression of the silent mating-type loci MAT2 and MAT3. May compact MAT2/3 into a heterochromatin-like conformation which represses the transcription of these silent cassettes.
  • 基因功能參考文獻：
    1. rather than promoting maintenance and spreading of heterochromatin, Swi6 appears to limit these processes and appropriately confine heterochromatin. PMID: 26438724
    2. binding of HP1 protein, Swi6, to methylated nucleosomes drives a switch from an auto-inhibited state to a spreading-competent state, where H3K9-methylated heterochromatin spreads to adjacent regions PMID: 23485968
    3. HP1(Swi6) mediates the recognition and destruction of heterochromatic RNA transcripts PMID: 22683269
    4. Mutations in Swi6 that disrupt cdc6 protein interaction disrupt silencing and delay replication in the centromere. PMID: 21239883
    5. Our analyses suggest that Swi6/HP1 recruits opposing chromatin-modifying activities, the balancing of which is crucial for heterochromatin maintenance. PMID: 16762840
    6. Binding of Swi6 within approx 50kb of the telomere occurs less in partial aneuploid strains compared to euploid strains of S. pombe. PMID: 18285637
    7. These results provide insights into the regulation of siRNA action and reveal roles for cis-dsRNA synthesis and HP1 in siRNA-mediated heterochromatin assembly. PMID: 18657501
    8. casein kinase II (CK2) phosphorylated Swi6 PMID: 19136623
    9. Msc1, is a critical factor required for proper cell fate determination in S. pombe. PMID: 19164572
    10. Swi6, an S. pombe counterpart of heterochromatin protein 1 (HP1), is required for early replication of the pericentromeric region and the mat locus. PMID: 19182789
    11. These analyses suggest that among other functions, HP1 proteins associate with chromatin-modifying factors that in turn cooperate to assemble repressive chromatin; thus, precluding accessibility of underlying DNA sequences to transcriptional machinery. PMID: 19443688

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：


主站蜘蛛池模板： 999国产精品999久久久久久| www亚洲精品久久久| 美女内射视频www网站午夜| 国内揄拍国内精品人妻| 女人和拘做受全程看视频| 久久ee热这里只有精品| 800av凹凸视频在线观看| 黑人大荫道bbwbbb高潮潮喷| 精品一区二区三区在线成人| 无码高潮少妇毛多水多水免费 | 人人爽人人爽人人片a| 动漫无遮挡羞视频在线观看| 成人无码精品免费视频在线观看| 双乳奶水饱满少妇呻吟| 日韩欧美在线综合网| 国产成人无码精品午夜福利a| 亚洲欧美日韩在线码| 99精品国产丝袜在线拍国语| 久青草久青草视频在线观看| 免费人成激情视频在线观看冫| 国产精品久久久久久久久久久久| 5x性社区免费视频播| 辽宁熟女高潮狂叫视频| 国产亚洲色欲色一色www| 国产疯狂伦交大片| 国产精品亚洲欧美大片在线看| 亚洲精品成人a在线观看| 人妻熟女av一区二区三区| 性色av一区二区三区人妻| 人禽伦免费交视频播放| 色爱区综合五月激情| 午夜免费啪视频在线18| 中文字幕人妻被公上司喝醉506| 精品无码专区毛片| 久久精品女人天堂av| 亚洲成国产人片在线观看| 久久久免费无码成人影片| 亚洲国产精品成人久久| 男人女人午夜视频免费| 日本中文字幕乱码aa高清电影| 亚洲另类欧美综合久久图片区|