在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Schizosaccharomyces pombe Alkyltransferase-like protein 1 (atl1)

Recombinant Schizosaccharomyces pombe Alkyltransferase-like protein 1 (atl1)

  • 中文名稱：
    Recombinant Schizosaccharomyces pombe Alkyltransferase-like protein 1(atl1)
  • 貨號(hào)：
    CSB-YP892425SXV
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Schizosaccharomyces pombe Alkyltransferase-like protein 1(atl1)
  • 貨號(hào)：
    CSB-EP892425SXV
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Schizosaccharomyces pombe Alkyltransferase-like protein 1(atl1)
  • 貨號(hào)：
    CSB-EP892425SXV-B
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Schizosaccharomyces pombe Alkyltransferase-like protein 1(atl1)
  • 貨號(hào)：
    CSB-BP892425SXV
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Schizosaccharomyces pombe Alkyltransferase-like protein 1(atl1)
  • 貨號(hào)：
    CSB-MP892425SXV
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    atl1
  • Uniprot No.：
  • 別名：
    atl1; SPAC1250.04cAlkyltransferase-like protein 1
  • 種屬：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-108
  • 氨基酸序列
    MRMDEFYTKV YDAVCEIPYG KVSTYGEIAR YVGMPSYARQ VGQAMKHLHP ETHVPWHRVI NSRGTISKRD ISAGEQRQKD RLEEEGVEIY QTSLGEYKLN LPEYMWKP
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in DNA damage recognition. Binds DNA containing O(6)-methylguanine and larger O(6)-alkylguanine adducts. The DNA is bent, the damaged base is rotated out of the DNA duplex into a hydrophobic binding pocket (nucleotide flipping), with Arg-39 donating a hydrogen bond to the orphaned cytosine to stabilize the extrahelical DNA conformation. This structural change in DNA presents the lesion to the nucleotide excision repair (NER) pathway. The affinity for O(6)-alkylguanine adducts increases with the size of the alkyl group. Low affinity small O(6)-alkylguanines are directed to the global genome repair pathway of NER via rhp7-rhp16 and rhp41-rhp23, while strong binding to bulky O(6)-alkylguanines stalls the transcription machinery and diverts the damage to the transcription-coupled repair pathway of NER via rhp26.
  • 基因功能參考文獻(xiàn)：
    1. Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-pi interactions. PMID: 23112169
    2. Data show that alkyltransferase-like 1 (Atl1)can play a pivotal role in selecting a specific nucleotide excision repair (NER) pathway, depending on the nature of the DNA modification. PMID: 22658721
    3. Atl1 may act by binding to O6-alkylguanine lesions and signalling them for processing by DNA repair pathways. PMID: 16679453
    4. Schizosaccharomyces pombe ATL structures without and with damaged DNA containing the endogenous lesion O(6)-methylguanine or cigarette-smoke-derived O(6)-4-(3-pyridyl)-4-oxobutylguanine PMID: 19516334
  • 蛋白家族：
    MGMT family, ATL subfamily
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 2021国产精品自在自线| 国产成人精品手机在线观看| 精品国产av一区二区三区| 亚洲女人被黑人巨大进入| 国产成人精品一区二三区在线观看| 西西人体大胆瓣开下部毛茸茸| 最新网站亚洲人成无码| 欧美成 人 在线播放视频 | 老色鬼在线精品视频| 精品国产一区二区三区四区阿崩| 亚洲 激情 小说 另类 欧美| 日韩精品无码人妻一区二区三区| 伊人精品成人久久综合97| 久久av一区二区三区| 国产精品国产三级国产aⅴ下载| 亚洲龙腾成小说人网| 亚洲第一狼人伊人av| 夜夜高潮夜夜爽夜夜爱| 国产成人无码av| 亚拍精品一区二区三区探花| 丰满的少妇被猛烈进入白浆 | 国产美女自卫慰水免费视频| 牲交a欧美牲交aⅴ免费一| 又色又爽又高潮免费视频观看| 一本色综合网久久| 樱花草在线社区www日本影院| 国产尤物在线视精品在亚洲| 两个人看的www免费视频中文| 成人综合网站| 欧美成人精精品一区二区| 白嫩少妇bbw撒尿视频| 人人妻人人澡人人爽不卡视频 | 亚洲乱妇老熟女爽到高潮的片| 国产成人免费ā片在线观看| 乱中年女人伦av二区| 午夜毛片不卡高清免费看| 亚洲人成在线影院| 国产精品爱啪在线播放| 人人妻人人澡人人爽欧美精品 | 日本人妻精品免费视频| 免费无码又爽又刺激网站|