Recombinant Salmonella typhimurium Secreted effector protein sptP (sptP), partial

中文名稱：

鼠傷寒沙門菌sptP重組蛋白
貨號：

CSB-YP301061SXB
規(guī)格：
來源：

Yeast
其他：

中文名稱：

鼠傷寒沙門菌sptP重組蛋白
貨號：

CSB-EP301061SXB
規(guī)格：
來源：

E.coli
其他：

中文名稱：

鼠傷寒沙門菌sptP重組蛋白
貨號：

CSB-EP301061SXB-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

鼠傷寒沙門菌sptP重組蛋白
貨號：

CSB-BP301061SXB
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

鼠傷寒沙門菌sptP重組蛋白
貨號：

CSB-MP301061SXB
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

sptP
Uniprot No.：

P74873
別名：

sptP; STM2878; Secreted effector protein SptP [Includes: GTPase-activating protein; GAP); Tyrosine-protein phosphatase; EC 3.1.3.48)]
種屬：

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear.
基因功能參考文獻：
1. we suggest the possibility that residues 106-136 of SptP are important for complex formation with SicP by in vitro reconstitution experiments. PMID: 25209503
2. SptP functioned by dephosphorylating the vesicle fusion protein N-ethylmalemide-sensitive factor and by blocking phosphorylation of Syk PMID: 24332031
3. Translation of the effector sptP is coupled to that of its chaperone sicP, and in the absence of translational coupling, an inhibitory RNA structure prevents translation of sptP. PMID: 21801239
4. Direct SptP binding and specific dephosphorylation of the AAA+ ATPase valosin-containing protein (VCP/p97), a facilitator of cellular membrane fusion and protein degradation, enhanced pathogen replication in Salmonella-containing vacuoles. PMID: 19286132
亞細胞定位：

Secreted. Host cytoplasm. Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cytoplasm.
蛋白家族：

YopE family
數(shù)據(jù)庫鏈接：

KEGG: stm:STM2878

STRING: 99287.STM2878