在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Salmonella typhimurium DNA-binding protein H-NS (hns)

Recombinant Salmonella typhimurium DNA-binding protein H-NS (hns)

  • 中文名稱：
    鼠傷寒沙門菌hns重組蛋白
  • 貨號：
    CSB-YP358108SXB
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    鼠傷寒沙門菌hns重組蛋白
  • 貨號：
    CSB-EP358108SXB
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    鼠傷寒沙門菌hns重組蛋白
  • 貨號：
    CSB-EP358108SXB-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    鼠傷寒沙門菌hns重組蛋白
  • 貨號：
    CSB-BP358108SXB
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    鼠傷寒沙門菌hns重組蛋白
  • 貨號：
    CSB-MP358108SXB
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    hns
  • Uniprot No.：
  • 別名：
    hns; hnsA; osmZ; STM1751DNA-binding protein H-NS; Histone-like protein HLP-II; Protein B1; Protein H1
  • 種屬：
    Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-137
  • 氨基酸序列
    SEALKILNN IRTLRAQARE CTLETLEEML EKLEVVVNER REEESAAAAE VEERTRKLQQ YREMLIADGI DPNELLNSMA AAKSGTKAKR AARPAKYSYV DENGETKTWT GQGRTPAVIK KAMEEQGKQL EDFLIKE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds tightly to dsDNA. Acts as a global transcriptional regulator through its ability to bind to AT-rich DNA sequences. Binds in the minor groove of AT-rich DNA. Was found to bind 746 genes, about half of which show no change in expression in disruption experiments suggesting these sites are important for nucleoid structure. On a global level genes bound by H-NS are expressed at a lower than average level; H-NS is excluded from binding to highly transcribed genes and does not co-localize with RNA polymerase in DNA-binding studies during exponential growth in rich medium. The best correlation for H-NS binding is AT-content rather than predicted DNA curvature. Has a strong preference for DNA that has been recently acquired by horizontal gene transfer, binding strongly to Salmonella pathogenicity islands 1 and 2 (SPI1 and SPI2); this offers the selective advantage of silencing foreign DNA while keeping it in the genome in case of need. DNA-binding influences plasmid DNA topology. For the proU locus (the proV-proW-proX operon) inhibits transcription at low osmolarity by binding to AT-rich, curved, DNA downstream of the transcription start site of proV; repression is greater when more than 1 curved DNA sequence is present. It plays a role in the thermal control of pili production. It is subject to transcriptional auto-repression. It binds preferentially to the upstream region of its own gene recognizing two segments of DNA on both sides of a bend centered around -150.
  • 基因功能參考文獻：
    1. Data suggest that Sfh acts as a molecular backup for H-NS and that it provides its 'stealth' function by replacing H-NS on the chromosome, thus minimizing disturbances to the H-NS-DNA binding pattern in cells that acquire pSfR27. PMID: 20444106
    2. The effects of heat on the oligomerization and gene regulating activity of HNS in S. typhimurium are reported. PMID: 15966862
    3. H-NS selectively silences horizontally acquired genes by targeting sequences with GC content lower than the resident genome; H-NS provides a previously unrecognized mechanism of bacterial defense against foreign DNA PMID: 16763111
    4. HilA promotes SPI4 expression by antagonizing the global transcriptional silencer H-NS. PMID: 18160484
    5. H-NS-like proteins have evolved to selectively target horizontally acquired and not core genome DNA. PMID: 19521501

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, nucleoid.
  • 蛋白家族：
    Histone-like protein H-NS family
  • 數據庫鏈接：

    KEGG: stm:STM1751

    STRING: 99287.STM1751



主站蜘蛛池模板： 日本japanese丰满多毛| 日韩欧美高清dvd碟片| 艳妇臀荡乳欲伦69调教视频| 图片区小说区激情区偷拍区| 天天综合色天天综合色h| 久久激情五月丁香伊人| 亚洲色大成网站www久久九九 | 激情综合色综合啪啪五月丁香 | 日本大胆欧美人术艺术| 亚洲一区二区三区波多野结衣| 亚洲精品久久午夜麻豆| 中文字幕一精品亚洲无线一区| 精品无码国产av一区二区| 久久久久人妻一区二区三区vr| 欧洲女人牲交性开放视频| 国产v片在线播放免费无遮挡| av无码免费永久在线观看| 精品黑人一区二区三区久久| 男女同房做爰爽免费| 小小拗女性bbwxxxx国产| 欧美另类 自拍 亚洲 图区| 熟女视频一区二区在线观看| 亚洲 日韩 欧美 成人 在线观看| 宅男66lu国产在线观看| 天堂va视频一区二区| 亚洲a∨无码男人的天堂| 日本一卡二卡不卡视频查询| 国产成人综合亚洲色就色 | 少妇熟女久久综合网色欲| 色欲狠狠躁天天躁无码中文字幕| 国产美女极度色诱视频www| 亚洲欧美日韩中文字幕在线一区| 日本久久久久久久久久加勒比| 欧美变态口味重另类在线视频| 动漫精品啪啪一区二区三区| 中国国产免费毛卡片| 99r在线精品视频在线播放| 久久狠狠色噜噜狠狠狠狠97| 国产精品白丝喷水在线观看| 亚洲在av人极品无码| 日产精品卡2卡三卡乱码网址|