在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saguinus oedipus Heat shock cognate 71 kDa protein (HSPA8), partial

  • 中文名稱:
    Recombinant Saguinus oedipus Heat shock cognate 71 kDa protein(HSPA8) ,partial
  • 貨號:
    CSB-YP761741SWB
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Saguinus oedipus Heat shock cognate 71 kDa protein(HSPA8) ,partial
  • 貨號:
    CSB-EP761741SWB
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Saguinus oedipus Heat shock cognate 71 kDa protein(HSPA8) ,partial
  • 貨號:
    CSB-EP761741SWB-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Saguinus oedipus Heat shock cognate 71 kDa protein(HSPA8) ,partial
  • 貨號:
    CSB-BP761741SWB
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Saguinus oedipus Heat shock cognate 71 kDa protein(HSPA8) ,partial
  • 貨號:
    CSB-MP761741SWB
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    HSPA8; IDBP1; Heat shock cognate 71 kDa protein; Heat shock 70 kDa protein 8; Intracellular vitamin D-binding protein 1
  • 種屬:
    Saguinus oedipus (Cotton-top tamarin)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The co-chaperones have been shown to not only regulate different steps of the ATPase cycle of HSP70, but they also have an individual specificity such that one co-chaperone may promote folding of a substrate while another may promote degradation. The affinity of HSP70 for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. HSP70 goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. The HSP70-associated co-chaperones are of three types: J-domain co-chaperones HSP40s (stimulate ATPase hydrolysis by HSP70), the nucleotide exchange factors (NEF) such as BAG1/2/3 (facilitate conversion of HSP70 from the ADP-bound to the ATP-bound state thereby promoting substrate release), and the TPR domain chaperones such as HOPX and STUB1. Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase STUB1.
  • 亞細胞定位:
    Cytoplasm. Melanosome. Cell membrane. Nucleus, nucleolus.
  • 蛋白家族:
    Heat shock protein 70 family


主站蜘蛛池模板: 亚洲爆乳无码专区www| 精品亚洲麻豆1区2区3区| 国产亚洲一区二区在线观看| 深夜国产一区二区三区在线看| 亚洲中文有码字幕日本第一页| 亚洲国产日韩制服在线观看 | 国产精品无码专区| 中文字幕无码中文字幕有码 | 国产精品白丝喷浆| 欧美真人做爰在线观看| 国产乡下妇女做爰| 丰满少妇被粗大的猛烈进出视频 | 可以直接免费观看的av网站| 在线视频夫妻内射| 日本一区二区三区不卡免费 | 午夜精品久久久久久久喷水| 日韩一区二区在线观看视频| 香蕉久久av一区二区三区app| 亚洲中字慕日产2020| 人妻少妇中文字幕乱码| 国产成人精品高清在线观看99| 一本精品99久久精品77| 国产最大成人亚洲精品| 国产人妻一区二区三区久| 亚洲中文字幕久在线| 国产亚洲视频在线观看网址| 97久久精品人人做人人爽| 性按摩xxxx在线观看| 日本毛茸茸的丰满熟妇| 日本免费一区二区三区四区五区| 成人性生交大片免费看视频app| 精品成人免费一区二区不卡| 亚洲 欧美 中文 日韩aⅴ| 中文字幕一精品亚洲无线一区 | 永久免费无码av在线网站| 免费人成在线观看视频高潮| 国产后入清纯学生妹| 日本欧美一区二区三区在线播放| 亚洲国产成人精品无码区在线 | 色婷婷久久综合中文久久一本| 秋霞午夜鲁丝片午夜精品|