在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae Transcriptional repressor OPI1 (OPI1)

Recombinant Saccharomyces cerevisiae Transcriptional repressor OPI1 (OPI1)

  • 中文名稱：
    釀酒酵母OPI1重組蛋白
  • 貨號：
    CSB-YP324292SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母OPI1重組蛋白
  • 貨號：
    CSB-EP324292SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母OPI1重組蛋白
  • 貨號：
    CSB-EP324292SVG-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母OPI1重組蛋白
  • 貨號：
    CSB-BP324292SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母OPI1重組蛋白
  • 貨號：
    CSB-MP324292SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    OPI1
  • Uniprot No.：
  • 別名：
    OPI1; YHL020C; Transcriptional repressor OPI1; Negative regulator of phospholipid biosynthesis; Overproducer of inositol protein 1
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-404
  • 氨基酸序列
    MSENQRLGLS EEEVEAAEVL GVLKQSCRQK SQPSEDVSQA DKMPASESST TPLNILDRVS NKIISNVVTF YDEINTNKRP LKSIGRLLDD DDDEHDDYDY NDDEFFTNKR QKLSRAIAKG KDNLKEYKLN MSIESKKRLV TCLHLLKLAN KQLSDKISCL QDLVEKEQVH PLHKQDGNAR TTTGAGEDET SSDEDDDDEE FFDASEQVNA SEQSIVVKME VVGTVKKVYS LISKFTANSL PEPARSQVRE SLLNLPTNWF DSVHSTSLPH HASFHYANCE EQKVEQQQQQ QQQQQQQQLL QQQLLQQQQQ KRNKDGDDSA SPSSSVTANG KVLILAKESL EMVRNVMGVV DSTLGKAEEW VKQKQEVKEM IRERFLQQQQ QYRQQQQKDG NYVKPSQDNV DSKD
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Negative regulator of the transcriptional complex INO2-INO4 in response to phospholipid precursor availability. When precursors become limiting, OPI1 is retained at the endoplasmic reticulum (ER) and INO2-INO4 activates INO1 and other genes required for phospholipid biosynthesis, whereas abundant precursor availability results in targeting of OPI1 to the nucleus to repress transcription of these genes. Binds directly to phosphatidic acid, which is required for ER targeting and may act as sensing mechanism for precursor availability, as phosphatidic acid becomes rapidly depleted upon phospholipid biosynthesis.
  • 基因功能參考文獻(xiàn)：
    1. The work shows that transcriptional repressor Opi1p is redox-regulated and establishes a new mechanism of gene regulation involving Opi1p, which is important for adaptation to H2 O2 in yeast cells (Saccharomyces cerevisiae). PMID: 28581036
    2. This study demonstrated that Pho85 binds to Opi1 in vitro and in vivo and that this interaction is increased in the presence of high concentrations of phosphate. PMID: 27743455
    3. Opi1p dissociates from Scs2p after targeting to the nuclear membrane, making it possible to be released from the membrane quickly when phosphatidic acid levels decrease. PMID: 26590299
    4. genes of phospholipid biosynthesis are negatively regulated by repressor protein Opi1 when precursor molecules inositol and choline are available. Opi1-triggered gene repression is mediated by recruitment of the Sin3 corepressor complex. PMID: 22543816
    5. demonstrate that a physical association between the Yet complex and Scs2p-Opi1p is required for proper localization of the Opi1p repressor to endoplasmic reticulum membranes and subsequent INO1 derepression PMID: 21372176
    6. a rapid decrease in intracellular pH in response to glucose starvation regulated binding of phosphatidic acid to Opi1, that coordinately repressed phospholipid metabolic genes; this enabled coupling of membrane biogenesis to nutrient availability PMID: 20798321
    7. Two of the mutations in OPI1 (V343Q and S339F) provide genetic evidence for an interaction between Opi1p and the Ino2p activator since they reside in a region of Opi1p recently shown to interact with Ino2p in vitro. PMID: 16322993
    8. casein kinase II phosphorylation at Ser10 plays a role in stimulating the repression of INO1 when Opi1p was not in its most active state PMID: 16407309
    9. To better understand the mechanism of Opi1p repression, the viable yeast deletion set was screened to identify Opi(-) mutants. In total, 89 Opi(-) mutants were identified, of which 7 were previously known to have the Opi(-) phenotype. PMID: 16582425
    10. This study revealed that a transcription factor that controls INO1 expression, called Opi1p, participates in the regulation of mat formation. Opi1p appears to modulate mat formation by influencing the expression of FLO11. PMID: 16896211

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Endoplasmic reticulum. Nucleus. Note=Maintained at the endoplasmic reticulum by SCS2 (PubMed:12727870). In response to elevated inositol levels, translocates to the nucleus (PubMed:15192221).
  • 數(shù)據(jù)庫鏈接：

    KEGG: sce:YHL020C

    STRING: 4932.YHL020C



主站蜘蛛池模板： 午夜福利免费0948视频| 国产手机在线亚洲精品观看| 一本aⅴ高清一区二区三区| 果冻传媒亚洲区二期| аⅴ资源中文在线天堂| 少妇精品导航| 女m羞辱调教视频网站| 国产精品成人午夜久久| 澳门永久av免费网站| 在线播放无码后入内射少妇| 一区二区三区鲁丝不卡麻豆| 2020精品国产a不卡片| 国产精品老热丝在线观看| 永久免费观看美女裸体的网站| 日韩精品无码免费专区午夜不卡| 色窝窝免费播放视频在线| 亚洲成av人的天堂在线观看| 免费无码不卡视频在线观看| 精品少妇人妻av久久久| 亚洲综合激情七月婷婷| 亚洲精品一区三区三区在线观看| 99久久久无码国产精品试看| 香蕉97超级碰碰碰视频| 印度女人狂野牲交| 欧美日韩一区二区三区视频播放| 亚洲国产成人久久综合人| 精品亚洲卡一卡2卡三卡乱码| 粗大的内捧猛烈进出在线视频| 亚洲午夜精品a片久久www慈禧| 精品国内综合一区二区| 国产成人高清精品亚洲| 免费精品国产人妻国语| 老司机导航亚洲精品导航| 亚洲精品久久久久国产剧8| 免费欧洲美女牲交视频| 久久精品国产一区二区三区| www亚洲精品久久久乳| 狠狠噜狠狠狠狠丁香五月| 精品综合久久久久久8888| 情侣作爱视频网站| 精品无人区一区二区三区在线|