在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saccharomyces cerevisiae Protein SIS1 (SIS1)

  • 中文名稱:
    釀酒酵母SIS1重組蛋白
  • 貨號:
    CSB-YP326198SVG
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    釀酒酵母SIS1重組蛋白
  • 貨號:
    CSB-EP326198SVG
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    釀酒酵母SIS1重組蛋白
  • 貨號:
    CSB-EP326198SVG-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    釀酒酵母SIS1重組蛋白
  • 貨號:
    CSB-BP326198SVG
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    釀酒酵母SIS1重組蛋白
  • 貨號:
    CSB-MP326198SVG
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SIS1
  • Uniprot No.:
  • 別名:
    SIS1; YNL007C; N2879; Protein SIS1
  • 種屬:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-352
  • 氨基酸序列
    MVKETKLYDL LGVSPSANEQ ELKKGYRKAA LKYHPDKPTG DTEKFKEISE AFEILNDPQK REIYDQYGLE AARSGGPSFG PGGPGGAGGA GGFPGGAGGF SGGHAFSNED AFNIFSQFFG GSSPFGGADD SGFSFSSYPS GGGAGMGGMP GGMGGMHGGM GGMPGGFRSA SSSPTYPEEE TVQVNLPVSL EDLFVGKKKS FKIGRKGPHG ASEKTQIDIQ LKPGWKAGTK ITYKNQGDYN PQTGRRKTLQ FVIQEKSHPN FKRDGDDLIY TLPLSFKESL LGFSKTIQTI DGRTLPLSRV QPVQPSQTST YPGQGMPTPK NPSQRGNLIV KYKVDYPISL NDAQKRAIDE NF
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required for nuclear migration during mitosis. It is required for the normal initiation of translation. Might mediate the dissociation of a specific protein complex of the translation machinery. Essential for viability.
  • 基因功能參考文獻:
    1. Differences in sensitivity of prion fragmentation to Sis1 and in relative inputs of fragmentation and malpartition in prion propagation result in opposite effects of Sis1 relocalization on [PSI (+)] and [URE3]. PMID: 28932898
    2. Sis1 plays a role in prion replication. PMID: 25329162
    3. Interaction of Sis1 with EEVD(Hsp70) minimizes transfer of Sis1-bound clients to Hsp70s that are primed for client transfer to folding and translocation pathways by their preassociation with EEVD binding adaptor proteins. PMID: 25687964
    4. This conservation of function is also prion-variant dependent, indicating that only one of the two Sis1-prion functions may have been maintained in eukaryotic chaperone evolution. PMID: 25058638
    5. The stability of Sis1 and mutants that had the central domains (named Gly/Met rich domain and C-terminal Domain I) deleted or switched to those of Ydj1 were evaluated to gain insight into the role of these regions in the structure and function of Sis1. PMID: 23227221
    6. Sis1 is a yeast member of the Type II Hsp40s family and in a highly conserved alpha-helical N-terminal J-domain, a disordered middle region (divided into glycine/phenylalanine (G/F) and glycine/methionine (G/M) rich regions) and two C-terminal sub-domains. PMID: 22011374
    7. Functions of yeast Hsp40 chaperone Sis1p are dispensable for prion propagation but important for prion curing and protection from prion toxicity. PMID: 21555396
    8. Genetic experiments showed that Sis1 is an essential protein and apparently plays a functional role at assembly or disassembly of protein complexes. PMID: 17985367
    9. In vivo monitoring of the prion replication cycle reveals a critical role for Sis1 in delivering substrates to Hsp104. PMID: 19026788

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Note=Localized throughout the cell but is more concentrated at the nucleus.
  • 數據庫鏈接:

    KEGG: sce:YNL007C

    STRING: 4932.YNL007C



主站蜘蛛池模板: 妺妺窝人体色777777| 天天澡日日澡狠狠欧美老妇| 男人女人午夜视频免费| 精品国产美女av久久久久| 国产日产欧产精品精品免费| 无码av中文一区二区三区| 东北妇女xx做爰视频| 性欧美大战久久久久久久| 日本va欧美va精品发布 | 亚洲成av人片在线观看无码不卡| 99精品国产再热久久无毒不卡| 天堂av无码大芭蕉伊人av不卡| 男生白内裤自慰gv白袜男同| 国产免费踩踏调教视频| 亚洲日本va中文字幕久久| 少妇久久久久久久久久| 熟妇人妻午夜寂寞影院| 久久亚洲国产精品影院| 亚洲va中文字幕无码一二三区| 亚洲精品一区二区三区中文字幕 | 污污内射久久一区二区欧美日韩| 欧美熟妇性开放| 亚洲制服 视频在线观看| 边喂奶边中出的人妻| 国产极品粉嫩泬免费观看| 刺激一区仑乱| 98色婷婷在线| 久久婷婷五月综合中文字幕| 久久精品一区二区av999| 天堂www中文在线资源| 国产永久免费观看视频| 啊轻点内射在线视频| 无码人妻专区免费视频| 四虎成人精品无码| 狠狠色综合7777久夜色撩人| 欧美99久久无码一区人妻a片| 国内精品久久久久久久电影视| 亚洲大尺度无码专区尤物| 国产精品久久毛片av大全日韩| 最新永久无码av网址亚洲| 欧美成人高清视频a在线看|