在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saccharomyces cerevisiae Protein DOA1 (DOA1), partial

  • 中文名稱:
    釀酒酵母DOA1重組蛋白
  • 貨號:
    CSB-YP327478SVG
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    釀酒酵母DOA1重組蛋白
  • 貨號:
    CSB-EP327478SVG
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    釀酒酵母DOA1重組蛋白
  • 貨號:
    CSB-EP327478SVG-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    釀酒酵母DOA1重組蛋白
  • 貨號:
    CSB-BP327478SVG
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    釀酒酵母DOA1重組蛋白
  • 貨號:
    CSB-MP327478SVG
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    DOA1
  • Uniprot No.:
  • 別名:
    DOA1; UFD3; ZZZ4; YKL213CProtein DOA1; Degradation of alpha protein 1; Ubiquitin fusion degradation protein 3
  • 種屬:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Ubiquitin-binding protein involved in protein ubiquitination, sorting and degradation. Acts as a ubiquitinated substrate-recruiting adapter for chaperone ATPase CDC48 by binding mono- or polyubiquitin chains. Depending on the context, promotes or prevents proteasomal degradation of ubiquitinated proteins. Involved in the ubiquitin fusion degradation (UFD) pathway by promoting the degradation of ubiquitinated proteins. Involved in the mitochondria-associated degradation pathway (MAD) by promoting the degradation of several ubiquitinated membrane proteins. By competing with UFD2 to bind CDC48, prevents the multi-ubiquitination and subsequent degradation of UFD2-dependent substrates. Required for ribophagy, a process which relocalizes ribosomal particles into the vacuole for degradation in response to starvation. Involved in the ubiquitin-mediated sorting of membrane proteins into multivesicular bodies (MVBs). In addition, plays an essential role in maintaining cellular ubiquitin levels. May affect indirectly the degradation of ubiquitinylated proteins by regulating cellular ubiquitin levels.
  • 基因功能參考文獻:
    1. Small-angle X-ray scattering combined with molecular docking and biochemical analysis yield the solution structure of the Doa1/PFU:Hse1/SH3 complex and suggest that hydrogen bonding is a major determinant in the interaction of Doa1/PFU with Hse1/SH3. PMID: 24607902
    2. A structural comparison of Doa1 with Ufd2 revealed that they share a similar ARM-like repeat, supporting a model in which Doa1 and Ufd2 compete for Cdc48 binding and may dictate the fate of ubiquitinated proteins in the proteasome pathway PMID: 21063153
    3. The data suggest that Doa1 is the major source of ubiquitin for the DNA damage response and that Doa1 also plays an additional essential and more specific role in the monoubiquitination of histone H2B. PMID: 16705165
    4. DOA1/UFD3 plays a role in sorting ubiquitinated membrane proteins into multivesicular bodies PMID: 18508771
  • 亞細胞定位:
    Nucleus. Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    WD repeat PLAP family
  • 數(shù)據(jù)庫鏈接:

    KEGG: sce:YKL213C

    STRING: 4932.YKL213C



主站蜘蛛池模板: 亚洲中文字幕久在线| 中国无码人妻丰满熟妇啪啪软件| 玩弄少妇人妻中文字幕| 亚洲欧美激情精品一区二区| 丰满少妇人妻久久久久久| 国产精品人成在线播放新网站| 风韵丰满熟妇啪啪区老老熟女百度| 亚洲色爱图小说专区| 巨胸不知火舞露双奶头无遮挡| 国产人澡人澡澡澡人碰视频| 永久免费观看的毛片手机视频| 人妻熟女一区二区aⅴ水野朝阳| 国内揄拍国内精品少妇| 成人性生交片无码免费看| 精品久久久久中文字幕加勒比| 国产成年码av片在线观看| 久久午夜无码鲁丝片| 西西人体做爰大胆gogo| 失禁潮痉挛潮喷av在线无码 | 国产精品成人永久在线四虎| 无套内射chinesehd熟女| 爱久久av一区二区三区| 97色伦图片97综合影院| 久久香综合精品久久伊人| av无码av在线a∨天堂app| 国产成人精品一区二三区| 免费超爽大片黄| 国产欧美在线一区二区三| 成人亚洲a片v一区二区三区动漫 | 亚洲在av人极品无码| 2021麻豆剧传媒一二三区| 欧美肥婆姓交大片| 高潮内射免费看片| 精品免费国产一区二区| 4444亚洲人成无码网在线观看 | 在线偷着国产精选视频| 少妇极品熟妇人妻200片| 国产亚洲产品影市在线产品| 国产真实乱对白精彩| 久久午夜色播影院| 撕开奶罩揉吮奶头视频|