在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saccharomyces cerevisiae Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 (SLM1), partial

  • 中文名稱:
    釀酒酵母SLM1重組蛋白
  • 貨號:
    CSB-YP328123SVG
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    釀酒酵母SLM1重組蛋白
  • 貨號:
    CSB-EP328123SVG
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    釀酒酵母SLM1重組蛋白
  • 貨號:
    CSB-EP328123SVG-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    釀酒酵母SLM1重組蛋白
  • 貨號:
    CSB-BP328123SVG
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    釀酒酵母SLM1重組蛋白
  • 貨號:
    CSB-MP328123SVG
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SLM1
  • Uniprot No.:
  • 別名:
    SLM1; LIT2; YIL105C; Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1; Synthetic lethal with MSS4 protein 1; TORC2 effector protein SLM1
  • 種屬:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Together with SLM2, effector of the TORC2- and calcineurin-signaling pathways. Phosphorylated and activated by TORC2 under favorable growth conditions. Mediates actin polarization via inhibition of calcineurin-dependent transcription. Upon nutrient limitation or environmental stress, gets dephosphorylated by calcineurin. Dephosphorylation inhibits its interaction with TORC2, thereby antagonizing TORC2 signaling and mediating calcineurin-dependent actin depolarization. Also functions in heat-induced, calcineurin-mediated uracil permease (FUR4) endocytosis.
  • 基因功能參考文獻:
    1. Slm1/Slm2 and TORC2-dependent phosphorylation of Ypk1 is coupled to the biosynthesis of complex sphingolipids and to their levels within the plasma membrane. PMID: 22895050
    2. Slm proteins are required for proper eisosome organization, endocytic trafficking and recycling in the yeast Saccharomyces cerevisiae. PMID: 21451250
    3. Slm1 and Slm2 integrate inputs from the Phosphatidylinositol-4,5-bisphosphate and TORC2 to modulate polarized actin assembly and growth PMID: 15689497
    4. calcineurin may modulate sphingolipid-dependent events through regulation of Slm1 and Slm2 PMID: 16738335
    5. Data suggest that Slm1 and Slm2 define a molecular link between phosphoinositide and sphingolipid signaling and thereby regulate actin cytoskeleton organization. PMID: 16847337
    6. Slm proteins are subject to regulation by multiple signals, including PI4,5P(2), TORC2, and sphingolipids, and may thus integrate inputs from different signaling pathways to temporally and spatially control actin polarization PMID: 17101780

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to cortical punctate structures. Correct localization requires phosphatidylinositol 4,5-bisphosphate and functional TORC2.
  • 數據庫鏈接:

    KEGG: sce:YIL105C

    STRING: 4932.YIL105C



主站蜘蛛池模板: 狠狠躁夜夜躁人人躁婷婷| 真实国产老熟女无套中出| 99精品视频在线观看| 国产成人午夜福利在线观看视频| 末成年毛片在线播放| 人妻丰满熟av无码区hd| 国产日韩在线时看高清视频| 天堂网www在线资源中文| 国产成+人+综合+亚洲专区| 亚洲国产无套无码av电影| 麻花传媒在线mv免费观看视频| 成人网站免费观看入口| 亚洲成av大片大片在线播放| 亚洲色欲色欲www在线看| 亚洲欧美日韩精品久久| 国产色产综合色产在线视频| 久久精品成人欧美大片| 国内精品久久人妻互换| 成 年 人 黄 色 大 片大 全| 色猫咪av在线观看| 男女啪啪抽搐高潮动态图| 久久久久久久久888| 成人试看120秒体验区| 国产成人精品无码片区在线观看| 国产成人综合在线女婷五月99播放 | 欧美成人aaaa免费全部观看| 亚洲人成色77777在线观看大战p | 亚洲精品伊人久久久大香| 欧美性猛交aaaa片黑人| 色婷婷av一区二区三区之红樱桃| 免费毛片手机在线播放| aⅴ亚洲 日韩 色 图网站 播放 | 午夜一区一品日本| 亚洲熟悉妇女xxx妇女av | 高清一区二区三区日本久| 青青草国产久久精品| 欧美亚洲高清国产| 在线播放无码高潮的视频| 99久久国产露脸精品国产麻豆| 午夜大片男女免费观看爽爽爽尤物 | 国产 高潮 抽搐 正在播放|