在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae Mitotic spindle checkpoint component MAD2 (MAD2)

Recombinant Saccharomyces cerevisiae Mitotic spindle checkpoint component MAD2 (MAD2)

  • 中文名稱：
    釀酒酵母MAD2重組蛋白
  • 貨號：
    CSB-YP340327SVG
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母MAD2重組蛋白
  • 貨號：
    CSB-EP340327SVG
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母MAD2重組蛋白
  • 貨號：
    CSB-EP340327SVG-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母MAD2重組蛋白
  • 貨號：
    CSB-BP340327SVG
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母MAD2重組蛋白
  • 貨號：
    CSB-MP340327SVG
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    MAD2
  • Uniprot No.：
  • 別名：
    MAD2; YJL030W; J1256Mitotic spindle checkpoint component MAD2; Mitotic MAD2 protein
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-196
  • 氨基酸序列
    MSQSISLKGS TRTVTEFFEY SINSILYQRG VYPAEDFVTV KKYDLTLLKT HDDELKDYIR KILLQVHRWL LGGKCNQLVL CIVDKDEGEV VERWSFNVQH ISGNSNGQDD VVDLNTTQSQ IRALIRQITS SVTFLPELTK EGGYTFTVLA YTDADAKVPL EWADSNSKEI PDGEVVQFKT FSTNDHKVGA QVSYKY
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Central component of the spindle assembly checkpoint which is a feedback control that prevents cells with incompletely assembled spindles from leaving mitosis. Thought to be recruited to unattached kinetochores by MAD1. During checkpoint activity, MAD2 is relayed from the MAD1-MAD2 complex to the mitotic checkpoint complex (MCC). MCC and presumably the MAD2-CDC20 subcomplex inhibit the ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) by preventing its activation by CDC20.
  • 基因功能參考文獻：
    1. Mad2 recruitment to the kinetochore and it's role in the spindle assembly checkpoint PMID: 27280788
    2. the very same dimerization interface of Mad2 is required for two different, yet fundamental, consecutive steps of SAC signaling: at the kinetochores for priming Cdc20/Mad2 binding, away from kinetochores for stabilizing this complex PMID: 23000150
    3. Mad2 is an important meiotic cell cycle regulator that ensures the timely degradation of anaphase-promoting complex substrates and the proper orchestration of the meiotic divisions PMID: 21697504
    4. Mad2 prolongs DNA damage checkpoint arrest caused by a double-strand break via a centromere-dependent mechanism. PMID: 20096585
    5. Data demonstrate that Mad2p localization at nuclear pore complexes is sensitive to nuclear levels of Ran and suggest that release of Mad2p from NPCs is closely linked with spindle assembly checkpoint activation in yeast. PMID: 15701789
    6. Our biochemical and genetic evidence shows that the interaction of open and closed Mad2 is essential for the spindle assembly checkpoint and is conserved in evolution. PMID: 16818718
    7. results surpass previously formulated objections to the Mad2-template model and predict that the release of Mad2 from Cdc20 is an energy-driven process PMID: 19143472

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    MAD2 family
  • 數據庫鏈接：

    KEGG: sce:YJL030W

    STRING: 4932.YJL030W



主站蜘蛛池模板： 天天爱天天做天天做天天吃中文| 色偷偷色噜噜狠狠成人免费视频| 久久99精品久久久久婷婷| 欧美亚洲偷图色综合| av激情亚洲男人的天堂| 日韩亚洲欧美精品综合| 国内老熟妇对白xxxxhd| 亚州av综合色区无码一区| 欧美日韩精品一区二区视频| 欧美性狂猛xxxxx深喉| 亚洲精品无码鲁网中文电影| 青青草大香焦在线综合视频| 人妻少妇heyzo无码专区| 亚洲日产韩国一二三四区| 末成年女av片一区二区| 蜜桃视频无码区在线观看| 欧美成人家庭影院| 日本高清色www网站色噜噜噜 | 亲嘴扒胸摸屁股激烈网站 | 亚洲精品一区二区精华液| 国产3p露脸普通话对白| 中文字幕亚洲日韩无线码| 国产高清japanese在线播放e| 色老头精品午夜福利视频| 99精品人妻少妇一区二区| 亚洲精品一区| 亚洲一二三四2021不卡| 国产1卡二卡3卡四卡乱码视频| 蜜臀av在线观看| 小sao货水好多真紧h无码视频 | 国产成人精品三级在线影院| 国产精品人妻久久久久| 女厕偷窥一区二区三区| 欧洲日韩亚洲无线在码| 女高中生自慰污污网站| 亚洲a∨无码男人的天堂| 麻批好紧日起要舒服死了| 亚洲444kkkk在线观看| 国产偷窥熟女精品视频| 欧美一区二区三区激情| 亚洲国产成av人天堂无码|