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  4. Recombinant Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone CNS1 (CNS1)

Recombinant Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone CNS1 (CNS1)

  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone CNS1(CNS1)
  • 貨號：
    CSB-YP327218SVG
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone CNS1(CNS1)
  • 貨號：
    CSB-EP327218SVG
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone CNS1(CNS1)
  • 貨號：
    CSB-EP327218SVG-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone CNS1(CNS1)
  • 貨號：
    CSB-BP327218SVG
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone CNS1(CNS1)
  • 貨號：
    CSB-MP327218SVG
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CNS1
  • Uniprot No.：
  • 別名：
    CNS1; YBR155W; YBR1205Hsp70/Hsp90 co-chaperone CNS1; Cyclophilin seven suppressor 1; STI1 stress-inducible protein homolog
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-385
  • 氨基酸序列
    MSSVNANGGY TKPQKYVPGP GDPELPPQLS EFKDKTSDEI LKEMNRMPFF MTKLDETDGA GGENVELEAL KALAYEGEPH EIAENFKKQG NELYKAKRFK DARELYSKGL AVECEDKSIN ESLYANRAAC ELELKNYRRC IEDCSKALTI NPKNVKCYYR TSKAFFQLNK LEEAKSAATF ANQRIDPENK SILNMLSVID RKEQELKAKE EKQQREAQER ENKKIMLESA MTLRNITNIK THSPVELLNE GKIRLEDPMD FESQLIYPAL IMYPTQDEFD FVGEVSELTT VQELVDLVLE GPQERFKKEG KENFTPKKVL VFMETKAGGL IKAGKKLTFH DILKKESPDV PLFDNALKIY IVPKVESEGW ISKWDKQKAL ERRSV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Co-chaperone that binds to the molecular chaperones Hsp90 (HSC82 and HSP82) and Hsp70 (SSA1). Stimulates SSA1 ATPase activity, but not Hsp90 ATPase activity. Involved in only a subset of Hsp90 functions.
  • 基因功能參考文獻：
    1. overexpression of other co-chaperones further disrupts the essential functions of Cns1 and Sgt1. However, the specificity of the negative effects indicates that only a subset of co-chaperones competes with Sgt1 or Cns1 for binding to Hsp90. PMID: 24923785
    2. CNS1 binds intact ribosome. PMID: 25380751
    3. Cns1p, a cochaperone for Hsp70 and Hsp90 chaperones, is a strong inhibitor of TBSV replication. PMID: 24027337
    4. Cns1 is a potent cochaperone of Ssa1 PMID: 15044454
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    TTC4 family
  • 數據庫鏈接：

    KEGG: sce:YBR155W

    STRING: 4932.YBR155W



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