在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae HNRNP arginine N-methyltransferase (HMT1)

Recombinant Saccharomyces cerevisiae HNRNP arginine N-methyltransferase (HMT1)

  • 中文名稱：
    釀酒酵母HMT1重組蛋白
  • 貨號：
    CSB-YP339910SVG
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母HMT1重組蛋白
  • 貨號：
    CSB-EP339910SVG
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母HMT1重組蛋白
  • 貨號：
    CSB-EP339910SVG-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母HMT1重組蛋白
  • 貨號：
    CSB-BP339910SVG
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母HMT1重組蛋白
  • 貨號：
    CSB-MP339910SVG
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    HMT1
  • Uniprot No.：
  • 別名：
    HMT1; ODP1; RMT1; YBR034C; YBR0320; Protein arginine N-methyltransferase 1; EC 2.1.1.-; Major type I protein arginine N-methyltransferase; Type I PRMT; hnRNP arginine N-methyltransferase
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-348
  • 氨基酸序列
    MSKTAVKDSA TEKTKLSESE QHYFNSYDHY GIHEEMLQDT VRTLSYRNAI IQNKDLFKDK IVLDVGCGTG ILSMFAAKHG AKHVIGVDMS SIIEMAKELV ELNGFSDKIT LLRGKLEDVH LPFPKVDIII SEWMGYFLLY ESMMDTVLYA RDHYLVEGGL IFPDKCSIHL AGLEDSQYKD EKLNYWQDVY GFDYSPFVPL VLHEPIVDTV ERNNVNTTSD KLIEFDLNTV KISDLAFKSN FKLTAKRQDM INGIVTWFDI VFPAPKGKRP VEFSTGPHAP YTHWKQTIFY FPDDLDAETG DTIEGELVCS PNEKNNRDLN IKISYKFESN GIDGNSRSRK NEGSYLMH
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that catalyzes both the mono- and asymmetric (type I) dimethylation of the guanidino nitrogens of arginine residues in a variety of RNA-binding proteins such as heterogeneous nuclear ribonucleoproteins (hnRNPs) and small nuclear ribonucleoproteins (snRNPs). Methylates NAB2, NPL3, HRP1 and YRA1, shuttling hnRNPs involved in mRNA processing and export, facilitating their export out of the nucleus. Methylation of NPL3 weakens its interaction with THO2, a component of the TREX (transcription/export) complex important for transcriptional elongation and recruitment of mRNA export factors. Methylates the hnRNP HRB1, but does not influence its subcellular location. Methylates the nucleolar proteins GAR1, NOP1 and NSR1. Methylates the snRNP SNP1 and modulates the cotranscriptional recruitment of splicing factors. Dimethylates free histone H4 (HHF1/HHF2) at 'Arg-4' (H4R3me2a) and plays a role in preservation and establishment of silent chromatin domains. Mono- and dimethylates ribosomal protein S2 (RPS2) at 'Arg-11'. Methylates the catalytic subunit of the SWI/SNF chromatin-remodeling complex SNF2.
  • 基因功能參考文獻：
    1. Data suggest that Hmt1-based arginine methylation is required for Scd6 localization and function. PMID: 27776129
    2. Arginine methylation is a widespread modification, with Hmt1 being the major arginine methyltransferase in S. cerevisiae. PMID: 26572822
    3. the methyltransferase activity of Hmt1 on histone H3R2 requires reciprocal contributions from two Hmt1 molecules, suggesting an intermolecular trans-complementary mechanism by which Hmt1 dimer methylates its substrates PMID: 25715670
    4. Carried out a proteomic profiling experiment to comprehensively identify the physical interactors of Hmt1, the budding yeast homolog for human PRMT1. Snf2 was experimentally confirmed as a robust substrate of Hmt1 in vitro. PMID: 22997150
    5. Interactions between HMT1 and genes encoding components of the histone deacetylase complex Rpd3L, are reported. PMID: 22953000
    6. These results are suggestive of a role for Rmt1 in modifying the function of Rps2 in a manner distinct from that occurring in S. pombe and mammalian cells. PMID: 20035717
    7. Loss of Hmt1's catalytic activity results in dimethylated Arg-3 histone H4 occupancy across silent chromatin regions. PMID: 17158743
    8. Results reveal a functional connection between histone acetylation, methylation, and two of the responsible enzymes, Gcn5p and Hmt1p. PMID: 19358899

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family
  • 數據庫鏈接：

    KEGG: sce:YBR034C

    STRING: 4932.YBR034C



主站蜘蛛池模板： 国产极品久久久久久久久| 亚洲精品午夜无码专区| 欧美亚洲综合成人专区| 亚洲伊人情人综合网站| 久久午夜神器| 婷婷四房综合激情五月| 强迫大乳人妻中文字幕| 视频久re精品在线观看| 午夜视频在线瓜伦| 娇小萝被两个黑人用半米长| 成人影院yy111111在线| 国产成人18黄网站| 色狠狠成人综合网| 亚洲处破女av日韩精品| 亚洲国产精品成人精品无码区蜜臀 | 人牛交vide欧美xxxx| 亚洲 一区二区 在线| 99国产精品无码| 99久久精品日本一区二区免费| 国产色在线 | 国产| 国精产品48x国精产品| 精品国产乱码久久久久久婷婷| 中文人妻无码一区二区三区| 美女人妻激情乱人伦| 自拍偷在线精品自拍偷免费| 欧美老熟妇xb水多毛多| 亚洲人成网站在线播放影院在线| 久久久一本精品久久精品六六| 精品蜜臀久久久久99网站| 又黄又爽吃奶视频在线观看| 日本免码va在线看免费| 性饥渴少妇av无码毛片| 亚洲午夜av久久久精品影院| 国产成人亚洲综合网色欲网| 久久精品av国产一区二区| 影音先锋女人av鲁色资源网久久| 永久免费精品精品永久-夜色| 色哟哟免费视频播放网站| 国产精品一区二区av不卡| 久久精品无码一区二区无码| 狠狠色噜噜狠狠狠狠蜜桃|