在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae G1-specific transcriptional repressor WHI5 (WHI5)

Recombinant Saccharomyces cerevisiae G1-specific transcriptional repressor WHI5 (WHI5)

  • 中文名稱：
    釀酒酵母WHI5重組蛋白
  • 貨號：
    CSB-YP613228SVG
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母WHI5重組蛋白
  • 貨號：
    CSB-EP613228SVG
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母WHI5重組蛋白
  • 貨號：
    CSB-EP613228SVG-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母WHI5重組蛋白
  • 貨號：
    CSB-BP613228SVG
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母WHI5重組蛋白
  • 貨號：
    CSB-MP613228SVG
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    WHI5
  • Uniprot No.：
  • 別名：
    WHI5; YOR083W; YOR3116W; G1-specific transcriptional repressor WHI5
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-295
  • 氨基酸序列
    MSLRTPKRSR TSDEQEQEQE QEQVQNPDTH VNNEHQQRPG PTTLLSTPVR LKNGFGTPSP PSPPGITKSI TKSRRRPSTT SLQGIFMSPV NKRRVGITAH GRVYDHNDDG HESESEDDEN EEENENQKKY DGHVSMPLLP PTTPKSRRSE VFLSPSPRLR SPPTAARRST GERPIREISH TLRTRLNYAL VKLQNGWTDK TLPELETELA PAVQTPPRRY HNRFPDSADA GTSAHTAFLQ ALGGHPPREE ATAVETLMLL SSPTKKQQHR PVPATSAGEP TDETEPESDT EVETS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcriptional repressor that negatively regulates G1-specific, SBF- and MBF-dependent transcription. Binds via SBF to promoters of G1-specific genes to repress transcription in early G1. During G1, phosphorylated by cyclin-CDK CLN3-CDC28 and progressively hyperphosphorylated by CDK associated with other G1-cyclins, which leads to dissociation of WHI5 from SBF, activating SBF-dependent transcription in late G1. Elimination of CDK activity at the end of mitosis by the mitotic exit network (MEN) allows WHI5 to reassociate with SBF to again repress G1/S transcription.
  • 基因功能參考文獻：
    1. at its most fundamental level, size control in budding yeast results from the differential scaling of Cln3 and Whi5 synthesis rates with cell size PMID: 26390151
    2. study describes a protein motif, the GTB motif (for G1/S transcription factor binding), in Nrm1 and Whi5 that is required to bind to the transcription factors PMID: 23382076
    3. Cln3 regulates SBF by at least two different pathways, one involving the repressive protein Whi5, and the second involving Stb1. PMID: 19823669
    4. Mutational analysis of Whi5 determined that only four C-terminal CDK sites were necessary and sufficient for Whi5 inactivation when Swi6 cyclin dependent kinase sites were also mutated. PMID: 19172996
    5. nuclear export of Whi5 is driven by Whi5(51-167) and depends on the phosphorylation of specific Ser residues PMID: 19713766
    6. Chromatin immunoprecipitation experiments show that SBF, Whi5 and Stb1 recruit both Cdc28 and the Rpd3(L) histone deacetylase to G1 cyclin promoters. PMID: 19745812

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    WHI5/NRM1 family
  • 數據庫鏈接：

    KEGG: sce:YOR083W

    STRING: 4932.YOR083W



主站蜘蛛池模板： 天天爽天天爽天天片a| 思思99re6国产在线播放| 亚洲人成网站在线播放2019| 18禁黄网站禁片免费观看不卡| 欧美成人天天综合在线| 天天躁日日躁aaaaxxxx| 亚洲精品国偷拍自产在线观看蜜臀 | 波多野结衣中文字幕一区二区三区| 久久久精品人妻一区二区三区 | 把女邻居弄到潮喷的性经历| 国产精品熟女高潮视频| 在线中文字幕乱码英文字幕正常| 久久激情综合狠狠爱五月| 国产欧美亚洲日韩图片| 67194成是人免费无码| 国产99久久久国产精品免费看| 国产成+人+综合+亚洲 欧美| 成人影院yy111111| 午夜精品国产精品大乳美女| 伊人成年网站综合网| 亚洲综合小说专区图片| 久久高清超碰av热热久久| 精品无码人妻一区二区三区| 亚洲欧美一区二区三区在线| 成在人线av无码免费漫画| 熟女人妻av完整一区二区三区| 国产精品白浆无码流出| 麻豆国产精品va在线观看| 97无码免费人妻超级碰碰碰碰| 无码人妻av免费一区二区三区| 色吊丝av中文字幕| 久久超碰色中文字幕超清| 国产成人午夜在线视频a站| 一道久久爱综合久久爱| 色综合久久久久无码专区 | 欧美最猛黑人xxxx黑人猛交| av片亚洲国产男人的天堂| 亚洲成av人在线观看网站| 天天拍天天看天天做| 狠狠精品久久久无码中文字幕| 亚洲人成黄网站69影院|